Nephropathy Clinical Trials

2 recruiting

Frequently Asked Questions

Common questions about Nephropathy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Phase 3

Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)

Immunoglobulin A NephropathyIgAN
Alexion Pharmaceuticals, Inc.510 enrolled267 locationsNCT06291376
Recruiting

Family Investigation of Nephropathy and Diabetes (F.I.N.D.)

Diabetes MellitusAlbuminuriaDiabetic Kidney Disease+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)100,000 enrolled1 locationNCT00342927
Recruiting
Phase 1

Study of BHV-1400 in IgA Nephropathy

IgA Nephropathy
Biohaven Therapeutics Ltd.20 enrolled12 locationsNCT07054684
Recruiting
Phase 3

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Primary IgA Nephropathy
Novartis Pharmaceuticals540 enrolled161 locationsNCT04557462
Recruiting
Phase 1Phase 2

Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cell Therapy in Diabetic Nephropathy Patients: A Clinical Trial

Diabetic Nephropathy Type 2
PT. Prodia Stem Cell Indonesia10 enrolled1 locationNCT07396155
Recruiting
Phase 4

Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy

IgA Nephropathy
Calliditas Therapeutics AB60 enrolled38 locationsNCT06712407
Recruiting
Phase 1

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07305116
Recruiting

A Multi-center Open Label Prospective Study on Early Initiation of Targeted-release Formulation of Budesonide in Patients With Primary IgA Nephropathy

IgA Nephropathy (IgAN)Early Initial Therapy
Sichuan Provincial People's Hospital200 enrolled1 locationNCT06676007
Recruiting
Phase 2Phase 3

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

Heart FailureAcute Kidney InjuryPercutaneous Coronary Intervention+2 more
VA Office of Research and Development240 enrolled3 locationsNCT04982419
Recruiting

Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy

Multiple MyelomaAcute Kidney InjuryLight Chain Nephropathy
Brigham and Women's Hospital450 enrolled1 locationNCT06483139
Recruiting

Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Chronic Kidney DiseasesDiabetes Mellitus, Type 2Diabetic Nephropathy Type 2 - Uncontrolled
Medical College of Wisconsin330 enrolled1 locationNCT05692388
Recruiting
Phase 4

ACE Reno, Pico Cell Matrix and Its Effect on eGFR in Chronic Kidney Diseases

Chronic Kidney DiseaseDiabetic NephropathiesChronic Kidney Disease (Stages 4 and 5)+5 more
Ace Cells Lab Limited300 enrolled1 locationNCT07187713
Recruiting
Phase 2

Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy

Chemotherapy Induced Peripheral NeuropathyDrug-Induced Nephropathy
VM Therapeutics LLC16 enrolled1 locationNCT07072468
Recruiting
Phase 4

Nefecon and Ambrisentan in IgA Nephropathy

Chronic Kidney DiseaseIgA NephropathyProteinuria
The First Hospital of Jilin University129 enrolled1 locationNCT07030894
Recruiting
Not Applicable

Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease

Kidney InjuryRisk ReductionKidney Failure, Chronic+1 more
Odense University Hospital254 enrolled1 locationNCT05283512
Recruiting
Phase 4

Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy?

IgA NephropathyRenal Insufficiency, ChronicIgA Vasculitis+1 more
Christian Medical College, Vellore, India585 enrolled12 locationsNCT06676384
Recruiting

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

Kidney DiseasesDiabetic NephropathyKidney Failure, Chronic+2 more
The Rogosin Institute2,000 enrolled1 locationNCT01802034
Recruiting

APOL1 Genetic Testing in African Americans

Chronic Kidney DiseasesGenetic PredispositionNephropathy+2 more
St. Louis University600 enrolled1 locationNCT05656261
Recruiting

Proteogenomic Monitoring and Assessment of Kidney Transplant Recipients

Acute Rejection (AR) of Transplanted KidneyChronic Allograft Nephropathy (CAN)Interstitial Fibrosis (IF)+1 more
Northwestern University1,000 enrolled1 locationNCT01531257
Recruiting

Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease

Type 2 Diabetes Mellitus (T2DM)Chronic Kidney DiseaseDiabetic Nephropathy Type 2
The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine720 enrolled1 locationNCT06833541