Phase 3 NET Clinical Trials

19 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 119 of 19 trials

Recruiting
Phase 3

Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET

Somatostatin Receptor Positive (SSTR+)Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET)
Novartis Pharmaceuticals240 enrolled65 locationsNCT06784752
Recruiting
Phase 2Phase 3

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled33 locationsNCT07210723
Recruiting
Phase 2Phase 3

Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers

PharmacokineticsPharmacodynamicsInsulin Aspart
Amphastar Pharmaceuticals, Inc.60 enrolled1 locationNCT07560150
Recruiting
Phase 2Phase 3

Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome
Quoin Pharmaceuticals16 enrolled5 locationsNCT07538583
Recruiting
Phase 3

A Study of a Gadolinium-Based Contrast Agent (GBCA) for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Central Nervous System (CNS) Lesions

For Contrast-enhanced Magnetic Resonance Imaging (MRI) of Central Nervous System (CNS) Lesions
Shanghai Shengdi Pharmaceutical Co., Ltd250 enrolled2 locationsNCT07275814
Recruiting
Phase 2Phase 3

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor (pNET)Extra-Pancreatic Neuroendocrine Tumor (epNET)
Exelixis440 enrolled80 locationsNCT06943755
Recruiting
Phase 3

A Study of a Gadolinium-Based Contrast Agent (GBCA) for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Body Parts (Non-Central Nervous System) Lesions

For Contrast-enhanced Magnetic Resonance Imaging (MRI) of Abnormal Vascular Lesions in Body Regions Excluding the Central Nervous System (CNS)
Shanghai Shengdi Pharmaceutical Co., Ltd306 enrolled2 locationsNCT07275723
Recruiting
Phase 2Phase 3

Effect of Nutritional Ketosis on Alcohol Metabolism

Magnetic Resonance ImagingAlcohol DrinkingKetogenic Dieting+2 more
University of Pennsylvania20 enrolled1 locationNCT06065657
Recruiting
Phase 3

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Beta-ThalassemiaSickle Cell DiseaseHematologic Diseases+4 more
Vertex Pharmaceuticals Incorporated26 enrolled6 locationsNCT05477563
Recruiting
Phase 3

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc.39 enrolled11 locationsNCT06760546
Not Yet Recruiting
Phase 3Phase 4

Topical Dutasteride on Male pattern hairloss.

androgenetic alopecia
Eric Song - Reskin Medical20 enrolled1 locationACTRN12626000082303
Recruiting
Phase 3

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

Skin DiseasesEpidermolysis BullosaConnective Tissue Disease+7 more
Chiesi Farmaceutici S.p.A.6 enrolled6 locationsNCT06917690
Recruiting
Phase 3

Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine Tumors

Grade1-2 Advanced Midgut Neuroendocrine Tumors (NETs)
Grupo Espanol de Tumores Neuroendocrinos166 enrolled21 locationsNCT06878664
Recruiting
Phase 2Phase 3

Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome
Quoin Pharmaceuticals8 enrolled1 locationNCT06953466
Recruiting
Phase 3

ErythroPOietin Alfa to Prevent Mortality and Reduce Severe Disability in Critically Ill TRAUMA Patients

Traumatic Brain InjuryWounds and InjuriesTrauma+3 more
Australian and New Zealand Intensive Care Research Centre2,500 enrolled41 locationsNCT04588311
Recruiting
Phase 3

A Phase III Clinical Study to Compare the Safety and Efficacy of 177Lu-DOTATATE Injection and Long-acting Oxytrexine in Adult Patients With NETs

NETS Ga68 Lu177
HTA Co., Ltd.184 enrolled1 locationNCT07057622
Recruiting
Phase 2Phase 3

Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome

Netherton Syndrome
Quoin Pharmaceuticals20 enrolled4 locationsNCT05789056
Recruiting
Phase 3

Effect of GH on the Blastocyst Euploid Rate in AMA Patients

Preimplantation Genetic TestingGrowth HormoneAge, Parental
ShangHai Ji Ai Genetics & IVF Institute400 enrolled1 locationNCT05447208
Terminated
Phase 3

Genetic Risk Information Disclosure study.

Genetic mutations predisposing to breast, ovarian or colorectal cancer and methods of disclosing that information to relatives.
The Cancer Council Victoria40 enrolled1 locationACTRN12607000316404