Non-invasive ventilation Clinical Trials

11 recruitingLast updated: June 20, 2026

There are 11 actively recruiting non-invasive ventilation clinical trials across 10 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Brockville, Ontario, Canada, Groningen, Netherlands, Haifa, Israel. Updated daily from ClinicalTrials.gov.


Non-invasive ventilation Trials at a Glance

11 actively recruiting trials for non-invasive ventilation are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Brockville, Groningen, and Haifa. Lead sponsors running non-invasive ventilation studies include Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Gözde Nur Erkan, and Dr. Ram Manohar Lohia Hospital.

Browse non-invasive ventilation trials by phase

Treatments under study

About Non-invasive ventilation Clinical Trials

Looking for clinical trials for Non-invasive ventilation? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Non-invasive ventilation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Non-invasive ventilation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 2

A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

Chronic respiratory failureNon-invasive ventilationRespiratory Insufficiency+7 more
University of Pennsylvania48 enrolled3 locationsNCT07071935
Recruiting
Not Applicable

Monitoring Respiratory Muscle Function in Acute Respiratory Failure Patients on Non Invasive Respiratory Support

Non-invasive ventilationAcute Respiratory Failure (ARF)
Queen Mary University of London50 enrolled2 locationsNCT07423338
Recruiting

Comparison of Nasal Continuous Positive Airway Pressure (CPAP) Mask and Nasal Airway in Molar Tooth Extraction Under Deep Sedation

Deep SedationNon-invasive Ventilation SupportNasal Airway+2 more
Gözde Nur Erkan60 enrolled2 locationsNCT06436638
Recruiting
Not Applicable

Influence of Flow Rate Change on CO2 Levels During High Flow Nasal Ventilation (HFNV) in Preterm Infants.

Non-invasive ventilationRespiratory distress syndromePrematurity
Rambam Health Care Campus45 enrolled1 locationNCT06622902
Recruiting

An International Survey on the Use of NIV Outside the ICU

Non-invasive ventilationSafetyIntensive Care (ICU)
Dr. Ram Manohar Lohia Hospital400 enrolled1 locationNCT07157215
Recruiting
Phase 3

Non-invasive Ventilation and Dexmedetomidine in Critically Ill Adults

Non-invasive ventilation
St. Joseph's Healthcare Hamilton846 enrolled6 locationsNCT06259565
Recruiting
Not Applicable

Quality of Life and Quality of Sleep Studies in Children with Home Care Ventilation in the West of France

Non-invasive ventilationQuality of Life
University Hospital, Angers160 enrolled1 locationNCT05368662
Recruiting

Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach

Chronic respiratory failureNon-invasive ventilation
University Medical Center Groningen100 enrolled1 locationNCT05756387
Recruiting
Not Applicable

Optimization of Positive End Expiratory Pressure by Use of Pulmonary Ultrasound for Patients With Blunt Chest Trauma Treated by Non-Invasive Ventilation (Opti-PEP).

Non-invasive ventilationThoracic Injuries
University Hospital, Montpellier40 enrolled1 locationNCT06072339
Recruiting
Not Applicable

Telemonitoring Utility in the Process of Adaptation to Home Mechanical Ventilation (HMV)

Non-invasive ventilation
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau48 enrolled1 locationNCT06240637
Recruiting

Infection Control and Prevention with Non-Invasive Ventilation Equipment

Suppurative lung diseaseType 2 respiratory failure requiring non-invasive ventilationSleep disordered breathing treated with continuous positive airway pressure (CPAP)
Royal Prince Alfred Hospital20 enrolled1 locationACTRN12623000932662