Phase 4 Obstructive Clinical Trials
29 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 29 trials
Recruiting
Phase 4
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled58 locationsNCT07053423
Recruiting
Phase 4
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4
Endotype DIrected Treatment for OSA in Down Syndrome
Down SyndromeObstructive Sleep Apnea (OSA)
University of Arizona200 enrolled5 locationsNCT07280468
Recruiting
Phase 4
Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
Obstructive Sleep Apnea of Adult
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran50 enrolled1 locationNCT06380491
Recruiting
Phase 4
Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
Chronic Obstructive Pulmonary Disease (COPD)
Copenhagen Respiratory Research2,000 enrolled14 locationsNCT06892210
Recruiting
Phase 4
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
Chronic Obstructive Pulmonary Disease
Maria Joyera Rodríguez135 enrolled6 locationsNCT06334575
Recruiting
Phase 4
A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)
Symptomatic Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb50 enrolled31 locationsNCT07004972
Recruiting
Phase 4
Impact GLP-1 Agonists Following Bariatric
Diabetes MellitusMetabolic SyndromeHypertension+2 more
University of Missouri-Columbia150 enrolled1 locationNCT06132477
Recruiting
Phase 4
Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics
Obstructive Sleep Apnea
Children's Hospital Medical Center, Cincinnati120 enrolled1 locationNCT04991389
Not Yet Recruiting
Phase 3Phase 4
COMparative Pharmacotherapy And peRsonalised stratEgy in the management of Coronary Microvascular Dysfunction double blind randomised controlled Trial - Part 1
Angina with non obstructive coronary artery disease
Sydney Local Health District130 enrolled2 locationsACTRN12625001179426
Not Yet Recruiting
Phase 3Phase 4
COMparative Pharmacotherapy And peRsonalised stratEgy in the management of Coronary Microvascular Dysfunction double blind randomised controlled Trial - Part II
Angina with non obstructive coronary artery disease
Sydney Local Health District130 enrolled2 locationsACTRN12625001174471
Recruiting
Phase 4
CPAP Effect on the Polycythemia in Patients With Obstructive Sleep Apnea
Sleep Apnea, ObstructivePolycythemia
Hospital Universitario Ramon y Cajal182 enrolled1 locationNCT06089603
Recruiting
Phase 4
PEG3350 vs Senna After Urogyn Surgery
Obstructive Defecation SyndromePostoperative Constipation
St. Joseph's Health, New York254 enrolled1 locationNCT06825260
Recruiting
Phase 4
Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic Cardiomyopathy
Morten Steen Kvistholm Jensen100 enrolled4 locationsNCT05569382
Recruiting
Phase 4
ENavogliflozin DElivering Alleviation of Ventricular Diastolic Dysfunction in nonObstRuctive Hypertrophic CardioMyopathy
Nonobstructive Hypertrophic Cardiomyopathy
Yonsei University200 enrolled1 locationNCT06580717
Recruiting
Phase 4
Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA
SurgeryEsketamineDexmedetomidine+2 more
Peking University First Hospital100 enrolled1 locationNCT06566482
Recruiting
Phase 4
Chronic Airway Disease, Mucus Rheology and Exacerbations
Chronic Obstructive Pulmonary Disease
University Hospital, Montpellier72 enrolled3 locationsNCT04339270
Recruiting
Phase 4
Optimising Azithromycin Prevention Treatment in COPD to Reduce Exacerbations
Chronic Obstructive Pulmonary Disease
Dr Ian B Wilkinson1,311 enrolled1 locationNCT05772013
Completed
Phase 4
Trialling a double-dose of influenza vaccine to examine the efficacy of the influenza vaccination in patients with chronic obstructive pulmonary disease (COPD)
Influenza viral diseaseChronic Obstructive Pulmonary Disease
Princess Alexandra Hospital43 enrolled2 locationsACTRN12620000954921
Recruiting
Phase 4
The Effect of PAP on ISSHL Comorbided With OSA
Obstructive Sleep ApneaSudden Hearing Loss
Beijing Tsinghua Chang Gung Hospital102 enrolled1 locationNCT04192656