Phase 2 Oligometastatic Clinical Trials

23 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 23 trials

Recruiting
Phase 2

Niraparib Rechallenge After Surgery in Ovarian Cancer Patients With Oligometastatic Progression

Ovarian CancerOligometastatic DiseaseSerous Ovarian Tumor
MedSIR30 enrolled14 locationsNCT06180356
Recruiting
Phase 2

A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

Breast CancerMetastatic Breast CancerMetastatic Breast Carcinoma+2 more
Memorial Sloan Kettering Cancer Center46 enrolled8 locationsNCT05534438
Recruiting
Phase 2

Testing the Addition of the Drug Relugolix to the Usual Radiation Therapy for Advanced-Stage Prostate Cancer, The NRG Promethean Study

Stage IVB Prostate Cancer AJCC v8Prostate AdenocarcinomaOligometastatic Prostate Carcinoma+2 more
NRG Oncology194 enrolled239 locationsNCT05053152
Recruiting
Phase 2

A Randomized Trial of Maintenance Systemic Therapy After Radiation for Oligometastatic Renal Cell Carcinoma (ASTROs)

Oligometastatic Renal Cell Carcinoma
M.D. Anderson Cancer Center144 enrolled1 locationNCT06004336
Recruiting
Phase 2

Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma

Recurrent Prostate AdenocarcinomaOligometastatic Prostate Adenocarcinoma
Jonsson Comprehensive Cancer Center107 enrolled1 locationNCT07150715
Recruiting
Phase 2

PULSAR in Systemic Therapy for Pancreatic Cancer

Borderline Resectable Pancreatic Ductal AdenocarcinomaLocally Advanced Pancreatic Ductal AdenocarcinomaOligometastatic Pancreatic Ductal Adenocarcinoma
Samsung Medical Center47 enrolled1 locationNCT07269626
Recruiting
Phase 1Phase 2

Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer

Solid Tumor, AdultOligometastatic Disease
Gustave Roussy, Cancer Campus, Grand Paris58 enrolled2 locationsNCT06439888
Recruiting
Phase 2

Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment of Prostate Cancer

Prostate AdenocarcinomaOligometastatic Prostate Carcinoma
Mayo Clinic110 enrolled1 locationNCT06369610
Recruiting
Phase 2

TERPS Trial for de Novo Oligometastic Prostate Cancer

Prostate CancerOligometastatic Disease
University of Maryland, Baltimore122 enrolled9 locationsNCT05223803
Recruiting
Phase 2

Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC

Non-small Cell Lung CancerOligometastatic DiseaseDriver Mutation
Tata Memorial Hospital106 enrolled1 locationNCT05277844
Recruiting
Phase 2

Lu-PSMA for Oligometastatic Prostate Cancer Treated With STereotactic Ablative Radiotherapy

Oligometastatic Prostate Cancer
Peter MacCallum Cancer Centre, Australia92 enrolled3 locationsNCT05560659
Recruiting
Phase 2

Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer

Oligometastatic Prostate Cancer
Catherine Spina23 enrolled1 locationNCT05915442
Recruiting
Phase 2Phase 3

Maximal Tumor Eradication for Oligometastatic Prostate Cancer

Oligometastatic Prostate Cancer
RenJi Hospital120 enrolled1 locationNCT06972511
Recruiting
Phase 2

'SOURCE - LUNG' Stereotactic Ablative Radiation Therapy Of UltRaCEntral LUNG Tumours (SOURCE Lung)

NSCLC/Oligometastatic Cancer (Single Lung Lesion)
Cancer Trials Ireland68 enrolled2 locationsNCT04375904
Recruiting
Phase 2

High-Risk Metachronous Oligometastatic Prostate Cancer Trial

Prostate CancerOligometastatic Disease
University of Maryland, Baltimore88 enrolled1 locationNCT06212583
Recruiting
Phase 2

Iparomlimab and Tuvonralimab With Chemoradiation for the Treatment of Locally Recurrent and Oligometastatic Cervical Cancer

Cervical CancerOligometastaticNeoplasm Recurrence, Local
Shandong Cancer Hospital and Institute36 enrolled1 locationNCT06942416
Recruiting
Phase 2Phase 3

Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care

Oligometastatic Disease
National Medical Research Radiological Centre of the Ministry of Health of Russia100 enrolled1 locationNCT06556550
Recruiting
Phase 2

Consolidative Radiotherapy Combined With Camrelizumab and Chemotherapy for Oligometastatic Nasopharyngeal Carcinoma

Oligometastatic Disease
Jiangxi Provincial Cancer Hospital63 enrolled3 locationsNCT05128201
Recruiting
Phase 2

Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO)

Locally Advanced Prostate CancerOligometastatic Prostate Cancer
The First Affiliated Hospital of Xiamen University40 enrolled1 locationNCT06387056
Recruiting
Phase 2

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer

Gastroesophageal-junction CancerGastroesophageal Junction AdenocarcinomaMetastatic Cancer+6 more
Fudan University55 enrolled1 locationNCT06121700