Phase 2 Open Clinical Trials

122 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 122 trials

Recruiting
Phase 2

Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS)

Myelodysplastic SyndromesClonal Cytopenia of Undetermined Significance
Washington University School of Medicine16 enrolled1 locationNCT05483010
Recruiting
Phase 2

Phase II Study of QLC2519 in Pediatric Solid Tumor Participants

NeutropeniaFebrile Neutropenia (FN)Pediatric Malignant Solid Tumor
Qilu Pharmaceutical Co., Ltd.18 enrolled1 locationNCT07724756
Recruiting
Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4-PositiveT-Lymphocytopenia
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled1 locationNCT02015013
Recruiting
Phase 2

Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab

Warm Autoimmune Hemolytic AnemiaPrimary immune thrombocytopenia
Novartis Pharmaceuticals60 enrolled25 locationsNCT07039422
Recruiting
Phase 1Phase 2

Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

Immune Thrombocytopenic PurpuraITP - Immune ThrombocytopeniaWarm Autoimmune Hemolytic Anemia+1 more
CRISPR Therapeutics AG60 enrolled8 locationsNCT07549698
Recruiting
Phase 2

A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia (ITP)Primary Evans Syndrome (ES)
Novartis Pharmaceuticals164 enrolled5 locationsNCT07421167
Recruiting
Phase 2

SG301-SC Injection Safety Study in Subjects With Primary ITP Patients

Primary immune thrombocytopenia
Hangzhou Sumgen Biotech Co., Ltd.60 enrolled5 locationsNCT07710248
Recruiting
Phase 2

Efficacy and Safety Study of Romiplostim N01 for Cancer Treatment-induced Thrombocytopenia (CTIT) in the Treatment of Leukemia

Cancer Treatment-induced Thrombocytopenia (CTIT)
Anhui Provincial Hospital97 enrolled1 locationNCT06898983
Recruiting
Phase 2Phase 3

A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenic PurpuraITPIdiopathic Thrombocytopenic Purpura+4 more
argenx24 enrolled20 locationsNCT07194850
Recruiting
Phase 2

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

Immune Thrombocytopenia
Incyte Corporation56 enrolled40 locationsNCT07104565
Recruiting
Phase 2

Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

Normal Tension Glaucoma (NTG)Non-proliferative Diabetic Retinopathy (NPDR)Open-angle Glaucoma (OAG)
Qlaris Bio, Inc.14 enrolled1 locationNCT07354477
Recruiting
Phase 2

A Phase 2 Study Evaluating Olutasidenib in Patients With IDH1-mutated Clonal Cytopenia of Undetermined Significance and Lower-risk Myelodysplastic/Syndromes/Chronic Myelomonocytic Leukemia.

Myelodysplastic SyndromesChronic Myelomonocytic LeukemiaClonal Cytopenia of Undetermined Significance
M.D. Anderson Cancer Center15 enrolled2 locationsNCT06566742
Recruiting
Phase 1Phase 2

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

NeutropeniaInfectionsWarts+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT00967785
Recruiting
Phase 1Phase 2

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia

Immune Thrombocytopenia (ITP)
Eli Lilly and Company68 enrolled45 locationsNCT06721013
Recruiting
Phase 2Phase 3

Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia

Systemic Lupus ErythematosusImmune Thrombocytopenia
Chinese SLE Treatment And Research Group164 enrolled1 locationNCT07657793
Recruiting
Phase 2

A Pilot Study of Efgartigimod for Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)

Immune-mediated Thrombotic Thrombocytopenic Purpura
University of Minnesota15 enrolled1 locationNCT06831058
Recruiting
Phase 2

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Severe Aplastic AnemiaAcquired Amegakaryocytic ThrombocytopeniaAcquired Pure Red Cell Aplasia+1 more
Masonic Cancer Center, University of Minnesota60 enrolled1 locationNCT06412497
Recruiting
Phase 2

Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial)

Myelodysplastic SyndromeClonal Cytopenia of Undetermined Significance
University of Colorado, Denver10 enrolled1 locationNCT07579429
Recruiting
Phase 2

Safety, Tolerability, and Efficacy of NVG-2089 in Participants With Immune Thrombocytopenia

Immune Thrombocytopenia (ITP)
Nuvig Therapeutics, Inc.30 enrolled1 locationNCT07095127
Recruiting
Phase 2

Enasidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH2A Decentralized Trial

Clonal Cytopenia of Undetermined SignificanceCCUS Clonal Cytopenia of Undetermined Significance
Washington University School of Medicine15 enrolled1 locationNCT06240754