Oropharynx Squamous Cell Carcinoma Clinical Trials

8 recruiting

Frequently Asked Questions

Common questions about Oropharynx Squamous Cell Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 2

A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

Squamous Cell Carcinoma of Head and NeckOral Cavity CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT07063212
Recruiting
Phase 2

First Line Weekly Chemo/Immunotherapy for Metastatic Head/Neck Squamous Cell Carcinoma Patients

Head & Neck CancerMetastatic Squamous Cell CarcinomaOropharynx Squamous Cell Carcinoma+3 more
Wake Forest University Health Sciences32 enrolled1 locationNCT04858269
Recruiting
Phase 2

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

Head and Neck CancerHead and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
University of Maryland, Baltimore61 enrolled5 locationsNCT06088381
Recruiting
Phase 2

SURVEILLE-HPV: Evaluation of HPV16 Circulating DNA as Biomarker to Detect the Recurrence, in Order to Improve Post Therapeutic Surveillance of HPV16-driven Oropharyngeal Cancers

Oropharynx Squamous Cell Carcinoma
UNICANCER420 enrolled16 locationsNCT05582122
Recruiting
Not Applicable

Training Swallowing Initiation During Expiration

Head and Neck CancerDysphagiaOropharyngeal Dysphagia+1 more
Northwestern University88 enrolled2 locationsNCT05278039
Recruiting

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

Head and Neck Squamous Cell CarcinomaCarcinoma, Squamous CellOropharyngeal Squamous Cell Carcinoma+1 more
UNC Lineberger Comprehensive Cancer Center220 enrolled3 locationsNCT04564989
Recruiting
Phase 2

The Minimalist Trial-2

HPV-Related Oropharynx Squamous Cell Carcinoma
Washington University School of Medicine142 enrolled1 locationNCT06702033
Recruiting

Detection of Oral and Throat Cancers Using OralViome Cancer Testing System

Premalignant LesionOral Squamous Cell CarcinomaOropharynx Squamous Cell Carcinoma
Viome475 enrolled1 locationNCT05451303
Recruiting

Monitoring and Early Response Evaluation Using HPV DNA - A Study on Patients With HPV-positive Throat Cancer (MER-HPV)

Oropharynx Squamous Cell Carcinoma
Region Skane150 enrolled1 locationNCT05649865