Osteonecrosis Clinical Trials

6 recruiting

Osteonecrosis Trials at a Glance

13 actively recruiting trials for osteonecrosis are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Phase 2 with 3 trials, with the heaviest enrollment activity in New York, Istanbul, and Bruges. Lead sponsors running osteonecrosis studies include AZ Sint-Jan AV, Marmara University, and Centre Hospitalier Universitaire de Besancon.

Browse osteonecrosis trials by phase

About Osteonecrosis Clinical Trials

Looking for clinical trials for Osteonecrosis? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Osteonecrosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Osteonecrosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting

Screening for Biomarkers of Osteonecrosis of the Femoral Head

Osteonecrosis of the Femoral Head
The First Affiliated Hospital of Xinxiang Medical College300 enrolled1 locationNCT07545616
Recruiting
Phase 2

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

Sickle Cell DiseaseOsteonecrosisAvascular Necrosis+2 more
University of California, Davis30 enrolled1 locationNCT06016634
Recruiting

Exactech Shoulder Post Market Clinical Follow-up Study

Rheumatoid ArthritisInfectionsAnkylosing Spondylitis+6 more
Exactech20,000 enrolled38 locationsNCT05603728
Recruiting
Not Applicable

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

Osteonecrosis of the Femoral HeadAvascular Necrosis of the Femoral Head
Johns Hopkins University192 enrolled10 locationsNCT06123481
Recruiting
Not Applicable

Partial Synovectomy in Articular Side of Quadriceps Tendon Verified to Reduce Crepitus in Retrospective Study

Osteoarthritis, KneeRheumatoid Arthritis, KneeSpontaneous Osteonecrosis of Knee
Gangnam Severance Hospital78 enrolled1 locationNCT06129214
Recruiting
Phase 2

Human Amniotic Membrane (hAM) for Stage II Maxillomandibular Osteonecrosis Management

Osteonecrosis Due to Drugs, Jaw
Centre Hospitalier Universitaire de Besancon66 enrolled5 locationsNCT05664815
Recruiting

Therapeutic Exposures and Risk Factors in MRONJ

Medication-Related Osteonecrosis of Jaw
Marmara University250 enrolled1 locationNCT06430762
Recruiting

Immunological Parameters Between MRONJ Stages

Medication-Related Osteonecrosis of Jaw
Marmara University42 enrolled1 locationNCT06420284
Recruiting

PROMIS Evaluation Study

Perthes DiseaseOsteonecrosisOsteoarthritis, Hip+2 more
Bezirkskrankenhaus St. Johann in Tirol200 enrolled1 locationNCT05734651
Recruiting

Validation of the O-bridge Protocol: a Prospective, Multicenter Trial

Quality of LifeMandibular ReconstructionBenign or Malignant Tumour of the Oral Cavity+2 more
AZ Sint-Jan AV80 enrolled5 locationsNCT04007783
Recruiting

Prospective Registry of Prosthodontic Rehabilitation in Oncology Patients Undergoing Jaw Reconstruction

Head and Neck CancerOsteonecrosisOsteoradionecrosis
AZ Sint-Jan AV55 enrolled1 locationNCT02661139
Recruiting
Phase 1

A study to evaluate safety and feasibility of zoledronic acid to prevent joint complication (osteonecrosis) following chemotherapy for acute lymphoblastic leukemia or lymphoma in children and adolescents.

Osteonecrosis
Sydney Children's Hospital Network10 enrolled1 locationACTRN12613000512729
Recruiting
Phase 2

A randomised controlled trial of bisphosphonate therapy in osteonecrosis of the hip.

collapse femoral headosteonecrosis of the hip
University of Sydney/ Northern Clinical School120 enrolled1 locationACTRN12609000104257