Phase 1 Overweight and Obesity Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1Phase 2

A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity

Overweight and Obesity
Wave Life Sciences USA, Inc.296 enrolled6 locationsNCT06842186
Recruiting
Phase 1Phase 2

A Trial to Learn How Safe AZD9550 Monotherapy and Combined With AZD6234 is in People With or Without Type 2 Diabetes Who Are Living With Obesity and Overweight

Overweight and Obesity
AstraZeneca160 enrolled15 locationsNCT06151964
Recruiting
Phase 1

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin ResistanceNon-Alcoholic Fatty Liver DiseaseOverweight and Obesity+1 more
Columbia University32 enrolled1 locationNCT06354088
Recruiting
Phase 1

Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study

High Blood SugarOverweight and ObesityHigh Blood Pressure
University of Alberta28 enrolled1 locationNCT06555393
Recruiting
Phase 1

A Study to Investigate Safety, Tolerability and Pharmacokinetics of LAE103 or LAE103 in Combination With LAE102 in Healthy Overweight/Obese Participants

Overweight and Obesity
Laekna Limited104 enrolled1 locationNCT07230496
Recruiting
Phase 1

Safety, Tolerability, and Pharmacokinetics of a Single or Multiple Ascending Doses of CPX101

Overweight and Obesity
Guangzhou Chia Tai Innovative Pharmaceutical Co., Ltd.80 enrolled3 locationsNCT06545162
Completed
Phase 1

Early intervention of multiple home visits to prevent childhood obesity among a disadvantaged population: a home-based Randomised Controlled Trial

Childhood overweight and obesity
Health Promotion Service, Sydney South West Area Health Service782 enrolled1 locationACTRN12607000168459
Recruiting
Phase 1

The "Kids on Track" program

Childhood overweight and obesity
Queensland Health160 enrolled1 locationACTRN12606000382572