Parkinson's Clinical Trials

3 recruiting

Frequently Asked Questions

Common questions about Parkinson's clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 138 trials

Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled26 locationsNCT07284784
Recruiting

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

Parkinson's Disease
Boston Scientific Corporation1,500 enrolled84 locationsNCT02071134
Recruiting
Not Applicable

Adaptive DBS Algorithm for Personalized Therapy in Parkinson's Disease (ADAPT-PD) China Study

Parkinson's Disease
MedtronicNeuro62 enrolled5 locationsNCT07216976
Recruiting

A Study to Assess Change in Sleep Disturbances of Adult Participants With Advanced Parkinson's Disease Receiving Subcutaneous Foslevodopa/Foscarbidopa

Advanced Parkinson's Disease
AbbVie103 enrolled13 locationsNCT07284342
Recruiting

Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)

Parkinson's DiseaseParkinsonismFreezing of Gait+2 more
Tianjin Huanhu Hospital700 enrolled1 locationNCT07386015
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Parkinson's Disease
Hoffmann-La Roche900 enrolled66 locationsNCT07174310
Recruiting
Not Applicable

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

Parkinson's Disease (PD)Essential Tremor
Boston University Charles River Campus80 enrolled2 locationsNCT07455760
Recruiting
Phase 2

Imaging Depression in Parkinson's Disease

Major Depressive DisorderParkinson's Disease
Yale University120 enrolled1 locationNCT06402955
Recruiting

Shanghai Clinical Cohort - Parkinson's Disease (Reserve)

Multiple System AtrophyParkinson's Disease (PD)
Ruijin Hospital700 enrolled1 locationNCT07353463
Recruiting
Not Applicable

Sleep-specific DBS Therapy in Parkinson's Disease

DystoniaDeep Brain StimulationParkinson's Disease and Parkinsonism
University of Minnesota64 enrolled1 locationNCT05962489
Recruiting
Phase 1

SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

PARKINSON DISEASE (Disorder)Advanced Parkinson's Disease
Serina Therapeutics40 enrolled4 locationsNCT07422675
Recruiting
Not Applicable

Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

Mild Cognitive Impairment (MCI) AmnesticLewy Body Disease With Mild Cognitive ImpairmentParkinson's Disease With Mild Cognitive Impairment
Masaryk University70 enrolled1 locationNCT07449117
Recruiting
Not Applicable

The Influence of Vibrotactile Stimulation on Self-selected Walking Speed in People With Parkinson's Disease

Parkinson's Disease (PD)
Magnes AG16 enrolled1 locationNCT07308418
Recruiting
Phase 1Phase 2

A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

Parkinson's Disease
Sumitomo Pharma America, Inc.25 enrolled2 locationsNCT06753331
Recruiting
Not Applicable

Exploration of Differences in Metabolite Concentrations by 7Teslas NMR Spectroscopy in Striatum and Subthalamic Nuclei in de Novo Parkinsonian Patients and Control Subjects

Parkinson's Disease
University Hospital, Clermont-Ferrand44 enrolled2 locationsNCT04735172
Recruiting
Not Applicable

Efficacy of a Breathwork Practice (SKY) on Well-Being of Individuals With Parkinson's Disease (iPD) and Care Partners

Parkinson's Disease
Nova Southeastern University40 enrolled3 locationsNCT06581523
Recruiting
Phase 3

Pharmacologically Modulating the Noradrenergic Arousal System to Reduce Freezing of Gait in Parkinson's Disease: a Multi-centre and Multi-modal Approach

Parkinson's Disease (PD)Freezing of GaitFreezing of Gait Symptoms in Parkinson Disease
Radboud University Medical Center60 enrolled1 locationNCT07316296
Recruiting
Phase 2

IMPACT 360 for Parkinson's Disease

Parkinson's Disease (PD)REM Sleep Behavior Disorder
University of British Columbia60 enrolled1 locationNCT07443293
Recruiting
Not Applicable

Deep Brain Stimulation Therapy in Movement Disorders

Parkinson's Disease
National Institute of Neurological Disorders and Stroke (NINDS)300 enrolled1 locationNCT02119611
Recruiting
Phase 1

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

DementiaALSMild Cognitive Impairment+2 more
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873