Phase 2 Parkinson's Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 2Phase 3

A Study of Buntanetap in Participants With PD

Deep Brain StimulationParkinson's Disease (PD)
Annovis Bio Inc.500 enrolled27 locationsNCT07284784
Recruiting
Phase 1Phase 2

rTMS to Improve Cognition in Parkinson's

Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 2

Ketamine for Veterans With Parkinson's Disease

Parkinson's Disease
VA Office of Research and Development80 enrolled1 locationNCT06231563
Recruiting
Phase 2

A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease

Parkinson's Disease (PD)
GEN İlaç ve Sağlık Ürünleri A.Ş.45 enrolled1 locationNCT07322887
Recruiting
Phase 2

Imaging Depression in Parkinson's Disease

Major Depressive DisorderParkinson's Disease
Yale University120 enrolled1 locationNCT06402955
Recruiting
Phase 1Phase 2

A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease

Parkinson's Disease
Sumitomo Pharma America, Inc.25 enrolled2 locationsNCT06753331
Recruiting
Phase 2

IMPACT 360 for Parkinson's Disease

Parkinson's Disease (PD)REM Sleep Behavior Disorder
University of British Columbia60 enrolled1 locationNCT07443293
Recruiting
Phase 2

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

Parkinson's Disease (PD)
TrueBinding, Inc.62 enrolled14 locationsNCT06773962
Recruiting
Phase 2

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

Parkinson's Disease
Michael J. Fox Foundation for Parkinson's Research60 enrolled1 locationNCT07020026
Recruiting
Phase 2

Tenapanor in Synucleinopathy-Related Constipation

Parkinson's DiseaseSynucleinopathy
Cedar Valley Digestive Health Center30 enrolled1 locationNCT06460038
Not Yet Recruiting
Phase 2

A clinical trial of a prebiotic powder for symptoms of Parkinson’s disease

Parkinson's disease (constipation and cognitive decline)
University of Newcastle180 enrolled2 locationsACTRN12623001186640
Withdrawn
Phase 2

An open-label study of combination therapy of CNSA-001 with levodopa in patients with Parkinson's Disease for the treatment of motor and non-motor symptoms of Parkinson's Disease.

Parkinson's Disease
Censa Pharmaceuticals Australia Pty Ltd6 enrolled1 locationACTRN12620000671965
Completed
Phase 2

Therapeutic potential for intranasal levodopa in Parkinson’s Disease – Off Reversal (THOR 201)

Parkinson's Disease
Clinical Network Services (CNS) Pty Ltd32 enrolled5 locationsACTRN12618000427279
Not Yet Recruiting
Phase 2Phase 3

Investigating the effect of Rasagiline on freezing of gait in Parkinson’s disease using accelerometry and functional MRI.

Freezing of gait in Parkinson's disease
A/Prof Simon Lewis40 enrolled1 locationACTRN12614000355673
Not Yet Recruiting
Phase 2

Effect of supplementary oral L-tyrosin plus 5-hydroxytriptophan on severity of Parkinson's Disease; a clinical trial

Parkinson's Disease
Daniel F Fouladi153 enrolled1 locationACTRN12613001276741
Recruiting
Phase 2

Desmopressin for the Treatment of Orthostatic Hypotension and Excessive Nighttime Urination in Parkinson’s Disease

NocturiaParkinson's DiseaseOrthostatic Hypotension
John O'Sullivan20 enrolled1 locationACTRN12609000080224