pelvic organ prolapse Clinical Trials

45 recruitingLast updated: June 27, 2026

There are 45 actively recruiting pelvic organ prolapse clinical trials across 26 countries. Studies span Not Applicable. Top locations include Istanbul, Turkey (Türkiye), Durham, North Carolina, United States, New Haven, Connecticut, United States. Updated daily from ClinicalTrials.gov.


pelvic organ prolapse Trials at a Glance

45 actively recruiting trials for pelvic organ prolapse are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 26 trials, with the heaviest enrollment activity in Istanbul, Durham, and New Haven. Lead sponsors running pelvic organ prolapse studies include Ethicon, Inc., Assiut University, and Gaziosmanpasa Research and Education Hospital.

Browse pelvic organ prolapse trials by phase

Treatments under study

About pelvic organ prolapse Clinical Trials

Looking for clinical trials for pelvic organ prolapse? There are currently 36 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new pelvic organ prolapse trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about pelvic organ prolapse clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting

Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry

pelvic organ prolapseStress Urinary Incontinence
Ethicon, Inc.1,000 enrolled10 locationsNCT04829175
Recruiting
Not Applicable

The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.

Pelvic Organ Prolapse Vaginal SurgeryStress Urinary Incontinence in Women
Hospital General de Agudos J. M. Penna330 enrolled1 locationNCT07414849
Recruiting

Centered Surgery - Preoperative Counseling and Patient Satisfaction

pelvic organ prolapse
The Cleveland Clinic106 enrolled1 locationNCT07471464
Recruiting

GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study

pelvic organ prolapse
Ethicon, Inc.100 enrolled3 locationsNCT04829058
Recruiting
Not Applicable

Vaginal Vault Native Tissue Suspension

pelvic organ prolapse
Assiut University10 enrolled1 locationNCT07517965
Recruiting
Not Applicable

Evaluation of a Personalizable Pessary for Pelvic Organ Prolapse

Pelvic organ prolapse (POP)
University of Alberta43 enrolled1 locationNCT06954701
Recruiting
Not Applicable

The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation

Pelvic organ prolapse (POP)Urinary IncontinencePelvic Floor Muscle Training+5 more
Vastra Gotaland Region380 enrolled2 locationsNCT07430865
Recruiting

Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery

Pelvic organ prolapse (POP)Stress Urinary Incontinence (SUI)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine382 enrolled1 locationNCT07601282
Recruiting
Not Applicable

The Finnish Uterine Prolapse Surgery Trial (The Fin-UP Trial)

Pelvic organ prolapse (POP)Uterine ProlapsePelvic Organ Prolapse Vaginal Surgery
Tampere University Hospital426 enrolled6 locationsNCT07566949
Recruiting
Not Applicable

Accelerometer Measured Early Recovery After Prolapse Surgery

pelvic organ prolapsePelvic organ prolapse (POP)Pelvic Organ Prolapse Vaginal Surgery+1 more
NICHD Pelvic Floor Disorders Network288 enrolled7 locationsNCT07218016
Recruiting
Not Applicable

Poly-L-Lactic Acid for Vulvovaginal Tissue Regeneration

Pelvic organ prolapse (POP)Pelvic Floor DisorderCystocele
Cassandra Kisby20 enrolled1 locationNCT07544667
Recruiting
Not Applicable

POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment

pelvic organ prolapseProlapse
Medstar Health Research Institute218 enrolled9 locationsNCT06634459
Recruiting
Not Applicable

Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS

pelvic organ prolapseCystoceleCystocele and Incomplete Uterovaginal Prolapse
Charles University, Czech Republic592 enrolled8 locationsNCT05602246
Recruiting
Not Applicable

Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension

Pelvic organ prolapse (POP)Postoperative Pain
Erkan Gol58 enrolled1 locationNCT07440576
Recruiting
Not Applicable

Effects of Pelvic Floor Muscle Training With & Without Hypopressive Exercises

pelvic organ prolapse
Riphah International University51 enrolled1 locationNCT07440875
Recruiting
Not Applicable

Comparison of Outpatient Rehabilitation Versus Self-training for the Treatment and Prevention of Postpartum Pelvic Floor Dysfunction

Pelvic Floor DysfunctionPostpartum CarePostpartum Comfort+3 more
Vilnius University80 enrolled1 locationNCT07426770
Recruiting
Not Applicable

Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy

pelvic organ prolapseStress Incontinence Female
University of Alabama at Birmingham110 enrolled2 locationsNCT07008898
Recruiting
Not Applicable

Are There Benefits of Using Energy-based Devices for Opportunistic Salpingo-oophorectomy During Vaginal Hysterectomy Compared to a Standard Cold Approach?

Pelvic organ prolapse (POP)
Wolfson Medical Center70 enrolled1 locationNCT07379411
Recruiting
Not Applicable

Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study

Pelvic organ prolapse (POP)Pelvic Organ Prolapse Vaginal SurgeryMesh Reinforcement+1 more
University of Sao Paulo General Hospital86 enrolled1 locationNCT07359755
Recruiting
Not Applicable

AMBULAPSE STUDY Feasibility Study on Laparoscopic Double-mesh Sacrocolpopexy With or Without Robotic Assistance, in Female Patients Presenting With Symptomatic Pelvic Organ Prolapse, Based on an Outpatient Treatment Model.

pelvic organ prolapse
Centre Hospitalier Universitaire de Nice80 enrolled5 locationsNCT03764852