Peripheral arterial occlusive disease Clinical Trials

7 recruitingLast updated: May 5, 2026

There are 6 actively recruiting peripheral arterial occlusive disease clinical trials across 9 countries. Studies span Early Phase 1, Not Applicable, Phase 2. Top locations include Dendermonde, Belgium, Detmold, Germany, Genk, Belgium. Updated daily from ClinicalTrials.gov.


Peripheral arterial occlusive disease Trials at a Glance

6 actively recruiting trials for peripheral arterial occlusive disease are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Early Phase 1 with 2 trials, with the heaviest enrollment activity in Dendermonde, Detmold, and Genk. Lead sponsors running peripheral arterial occlusive disease studies include Aplagon Oy, OrbusNeich, and Paracelsus Medical University.

Browse peripheral arterial occlusive disease trials by phase

About Peripheral arterial occlusive disease Clinical Trials

Looking for clinical trials for Peripheral arterial occlusive disease? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peripheral arterial occlusive disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peripheral arterial occlusive disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 16 of 6 trials

Recruiting
Phase 2

Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic Limb-threatening Ischemia

Peripheral arterial occlusive diseaseChronic Limb Threatening Ischemia
Aplagon Oy42 enrolled3 locationsNCT07352800
Recruiting

VITUS Post-Market Registry

Peripheral arterial occlusive diseasePeripheral Arterial Disease
OrbusNeich284 enrolled13 locationsNCT06832631
Recruiting
Early Phase 1

Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease

Peripheral arterial occlusive diseasePeripheral Arterial DiseasePeripheral Vascular Diseases+1 more
University of Nebraska20 enrolled1 locationNCT06319339
Recruiting
Early Phase 1

Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography)

Peripheral arterial occlusive diseaseCritical Limb Ischemia
Aplagon Oy10 enrolled1 locationNCT06204237
Recruiting
Not Applicable

FRAMED Infrainguinal Venous Bypass Versus Conventional Autologous Bypass Trial

Peripheral arterial occlusive diseaseFemoropopliteal StenosisClaudication, Intermittent+2 more
Paracelsus Medical University110 enrolled1 locationNCT06082466
Recruiting
Not Applicable

Efficacy and Safety of the Regulatory Polypeptides in Patients With Peripheral Atherosclerosis.

Peripheral arterial occlusive disease
Ryazan State Medical University120 enrolled1 locationNCT05933720