pilonidal sinus Clinical Trials

12 recruitingLast updated: May 5, 2026

There are 16 actively recruiting pilonidal sinus clinical trials across 8 countries. Studies span Not Applicable, Phase 2, Phase 4. Top locations include Istanbul, Other, Turkey (Türkiye), Istanbul, Turkey (Türkiye), Castlebar, Ireland. Updated daily from ClinicalTrials.gov.


pilonidal sinus Trials at a Glance

16 actively recruiting trials for pilonidal sinus are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Istanbul, Istanbul, and Castlebar. Lead sponsors running pilonidal sinus studies include Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital, Aroa Biosurgery Limited, and Ankara Etlik City Hospital.

Browse pilonidal sinus trials by phase

Treatments under study

About pilonidal sinus Clinical Trials

Looking for clinical trials for pilonidal sinus? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new pilonidal sinus trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about pilonidal sinus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Not Applicable

Pediatric Pilonidal Sinus Surgical Treatment

pilonidal sinusSurgeryPediatric
Zeliha Alicikus80 enrolled1 locationNCT07369921
Recruiting

Phenol or Laser: Best Minimally Invasive Treatment for Pilonidal Sinus?

Surgical OutcomesPilonidal Sinus TreatmentPilonidal Sinus Disorder
Mersin University64 enrolled1 locationNCT06721169
Recruiting

Prospective Study in Laser Treatment of Pilonidal Cysts

pilonidal sinus
Centre Hospitalier Departemental Vendee240 enrolled2 locationsNCT07314632
Recruiting
Phase 2

Topical Anti-Androgens in Pilonidal Sinus Disease

Pilonidal Diseasepilonidal sinusPilonidal Disease of Natal Cleft+1 more
University of Pennsylvania75 enrolled1 locationNCT06286397
Recruiting

Myriad™ Augmented Soft Tissue Reconstruction Registry

pressure injurypilonidal sinusHidradenitis Suppurativa+4 more
Aroa Biosurgery Limited800 enrolled13 locationsNCT05243966
Recruiting
Not Applicable

The Effect of Local Anesthesia Techniques on Postoperative Pain After Laser Treatment of Pilonidal Sinus

Pilonidal Sinus DiseasePilonidal Sinus TreatmentPilonidal Cyst and Sinus Without Abscess+1 more
Opća županijska bolnica Požega100 enrolled1 locationNCT07408414
Recruiting

Factors Affecting Wound Dehiscence in Pilonidal Sinus Surgery (ORIPIS)

Pilonidal Sinus Disorder
Ankara Etlik City Hospital250 enrolled1 locationNCT07370714
Recruiting

Bascom Cleft Lift for Primary Wound Healing in Complex and Recurrent Sacrococcygeal Pilonidal Sinus Disease

pilonidal sinus
Albert Schweitzer Ziekenhuis, Netherlands58 enrolled1 locationNCT06683274
Recruiting
Not Applicable

Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus

Laser TherapyPilonidal Sinus Disease
Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital130 enrolled1 locationNCT07023952
Recruiting
Not Applicable

ENVELOP: Wound Care Following Pilonidal Sinus Surgery

pilonidal sinusWound Healing
Royal College of Surgeons, Ireland200 enrolled10 locationsNCT06647290
Recruiting

Comparison of Pit Picking, Phenol and Combined Pit Picking and Phenol Applications in Pilonidal Sinus Treatment

pilonidal sinus
Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital165 enrolled1 locationNCT06517472
Recruiting

Outcomes of Karydakis, Primary Closure, and Pit Picking Methods in the Treatment of Pilonidal Sinus: A Prospective Study in Women

pilonidal sinus
Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital145 enrolled1 locationNCT06518499
Recruiting
Not Applicable

The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease

pilonidal sinus
Necmi Kadıoğlu Hospital100 enrolled1 locationNCT06324656
Recruiting
Not Applicable

Pilonidal Sinus Disease

pilonidal sinus
Sohag University30 enrolled1 locationNCT06508086
Recruiting
Not Applicable

The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children

Pilonidal Diseasepilonidal sinus
Mustafa Azizoğlu120 enrolled1 locationNCT06391307
Recruiting
Phase 4

Comparison of the two treatment modalities (crystallized phenol application vs. surgical treatment) for pilonidal sinus disease

patients with pilonidal sinus disease
Kamil Gulpinar150 enrolled1 locationACTRN12612000868886