Phase 3 PME Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 3

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals320 enrolled109 locationsNCT06719141
Recruiting
Phase 3

Reducing Missed Appointments

Neurodevelopmental Disorders
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.5,000 enrolled1 locationNCT06915480
Recruiting
Phase 3

Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.100 enrolled17 locationsNCT07224581
Recruiting
Phase 3

TAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental Disorders

EpilepsyNeurodevelopmental Disorder (Diagnosis)GRIN-related Disorders+4 more
Meyer Children's Hospital IRCCS40 enrolled3 locationsNCT07377032
Recruiting
Phase 3

A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine

Developmental and Epileptic Encephalopathy 1
Praxis Precision Medicines160 enrolled5 locationsNCT07010471
Recruiting
Phase 3

The MOM-CARE Trial : Evaluating Antenatal and Postnatal MMSPlus for Improved Infant Birth and Growth Outcomes

Newborn HealthNeurodevelopment OutcomeMultiple Micronutrient Deficiencies During Pregnancy+3 more
Aga Khan University3,000 enrolled1 locationNCT07029282
Recruiting
Phase 3

Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma

AsthmaFractures, BoneAllergy+8 more
Professor Klaus Bønnelykke2,000 enrolled1 locationNCT06560255
Recruiting
Phase 3

VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma

AsthmaFractures, BoneAllergy+8 more
Professor Klaus Bønnelykke2,000 enrolled1 locationNCT06570889
Not Yet Recruiting
Phase 2Phase 3

Effectiveness and safety of riluzole for the treatment of seizures in individuals with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE).

SCN8A developmental and epileptic encephalopathy
University of Melbourne5 enrolled1 locationACTRN12625000845437
Recruiting
Phase 2Phase 3

Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior

HypoxiaNeurodevelopmental DisordersCongenital Heart Disease in Children+1 more
University of Utah150 enrolled5 locationsNCT05767385
Active
Phase 3

Benefits and safety of IRon supplementation with MAlaria chemoprevention to children in Malawi (IRMA) - A randomised controlled trial

Impaired child cognitive developmentStuntingMalaria+2 more
College of Medicine, University of Malawi2,168 enrolled1 locationACTRN12620000386932
Recruiting
Phase 3

The effects of vitamin D supplementation on bone density in vitamin D insufficient teenagers: randomised controlled trial

Bone development
Menzies Research Institute670 enrolled1 locationACTRN12608000299303