Phase 3 Pneumonia Clinical Trials

20 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 20 trials

Recruiting
Phase 3

AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia

Community-acquired Pneumonia
University of Manitoba4,000 enrolled64 locationsNCT05848713
Recruiting
Phase 3

Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive Ventilation

PneumoniaSeptic ShockThe Critically Ill Patient is Requiring Intubation
Helwan University41 enrolled1 locationNCT07530146
Recruiting
Phase 3

Randomised Evaluation of COVID-19 Therapy

Pneumonia
University of Oxford70,000 enrolled16 locationsNCT04381936
Recruiting
Phase 3

Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward

Community-acquired Pneumonia
Nantes University Hospital326 enrolled19 locationsNCT06229288
Recruiting
Phase 3

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

Community-acquired Pneumonia
Biotest590 enrolled147 locationsNCT05722938
Recruiting
Phase 3

Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia

Pneumocystis PneumoniaPneumocystisPneumocystis Jirovecii Infection+5 more
Todd C. Lee MD MPH FIDSA416 enrolled1 locationNCT04851015
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Meropenem and Pralurbactam in HABP/VABP

Hospital-acquired Bacterial Pneumonia and Ventilator-associated Bacterial Pneumonia
Qilu Pharmaceutical Co., Ltd.420 enrolled1 locationNCT07327619
Recruiting
Phase 2Phase 3

A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women

Neonatal SepsisPneumoniaInfections+6 more
Minervax ApS338 enrolled6 locationsNCT06592586
Recruiting
Phase 3

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT)

Community-acquired Pneumonia
Hellenic Institute for the Study of Sepsis330 enrolled24 locationsNCT06294600
Recruiting
Phase 3

Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL

Pneumonia, Viral
Jena University Hospital616 enrolled28 locationsNCT06134492
Recruiting
Phase 3

Human Recombinant Interferon Gamma in the Treatment of Ventilator-acquired Pneumonia in ICU Patients

Pneumonia, Ventilator-Associated
Hospices Civils de Lyon132 enrolled9 locationsNCT05843786
Recruiting
Phase 3

Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in Carbapenem-Resistant Enterobacteriaceae Infections

Hospital-acquired Bacterial Pneumonia (HABP)Ventilator-associated Bacterial Pneumonia (VABP)Complicated Intra-abdominal Infection (cIAI)+2 more
Qilu Pharmaceutical Co., Ltd.80 enrolled1 locationNCT07089186
Recruiting
Phase 2Phase 3

Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia.

Community-acquired Pneumonia
St. Justine's Hospital1,370 enrolled1 locationNCT03031210
Recruiting
Phase 3

Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery

PneumoniaSurgical Site InfectionInfection+1 more
University of Birmingham12,942 enrolled37 locationsNCT04256798
Recruiting
Phase 3

Study of Intravenous TAD® 600 Mg/4 ML Solution for Injection to Evaluate Efficacy and Safety in Preventing Myocardial Injury in Patients with Pneumonia.

PneumoniaMyocardial Injury
Biomedica Foscama S.p.A. Industria Chimico-Farmaceutica178 enrolled7 locationsNCT06296212
Recruiting
Phase 3

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Community-acquired Pneumonia, Influenza, COVID-19
UMC Utrecht20,000 enrolled408 locationsNCT02735707
Recruiting
Phase 3

A Phase 3b Randomized, Double-blind, Multi-center Study to Compare the Safety and Efficacy of Omadacycline to Moxifloxacin for Treating Adult Subjects With CABP

Community-acquired Bacterial Pneumonia
Zai Lab (Hong Kong), Ltd.100 enrolled40 locationsNCT06162286
Recruiting
Phase 3Phase 4

Enhanced community case management to increase access to pneumonia treatment

Pneumonia
World Health Organization4,700 enrolled4 locationsACTRN12617000857303
Recruiting
Phase 3

A Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Three-Arm Study to Evaluate the Safety and Efficacy of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) Administration in Subjects with Severe Community-Acquired Pneumonia

Severe Community-Acquired Pneumonia
Novartis Pharmaceuticals Corporation2,100 enrolled16 locationsACTRN12607000460404
Completed
Phase 3

A Phase 3, Randomized, Double-Blind, Parallel-Group, Multinational Trial of Intravenous Telavancin Versus Vancomycin for Treatment of Hospital-Acquired Pneumonia with a Focus on Patients with Infections Due to Methicillin-Resistant Staphylococcus aureus (ATTAIN I & ATTAIN II)

Hospital-Acquired Pneumonia
Theravance, Inc.750 enrolled1 locationACTRN12605000324617