Phase 2 Post Traumatic Stress Disorder Clinical Trials

19 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 119 of 19 trials

Recruiting
Phase 2

MDMA-Assisted Massed Exposure Therapy for PTSD

Post Traumatic Stress Disorder
Emory University200 enrolled1 locationNCT07288151
Recruiting
Phase 2

Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI

Traumatic Brain InjuryPost Traumatic Stress Disorder
NYU Langone Health120 enrolled1 locationNCT04550377
Recruiting
Phase 2

Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms

Post Traumatic Stress DisorderPTSD
Oui Therapeutics, Inc.40 enrolled1 locationNCT07316088
Recruiting
Phase 2

Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD.

Post Traumatic Stress Disorder
Massachusetts General Hospital96 enrolled1 locationNCT07079761
Recruiting
Phase 2Phase 3

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

DepressionPost Traumatic Stress DisorderAnxiety Disorders
University of California, San Diego128 enrolled1 locationNCT06273527
Recruiting
Phase 2Phase 3

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

Post Traumatic Stress DisorderMild Traumatic Brain InjuryAutonomic Nervous System Disease+2 more
Virginia Commonwealth University148 enrolled1 locationNCT07071350
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Master Protocol

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research800 enrolled10 locationsNCT05422612
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research200 enrolled10 locationsNCT05948540
Recruiting
Phase 2

Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine

Post Traumatic Stress Disorder
Global Coalition for Adaptive Research200 enrolled10 locationsNCT05948553
Recruiting
Phase 2

Suvorexant for Treatment of AUD and PTSD

InsomniaPost Traumatic Stress Disorder (PTSD)Alcohol Use Disorder (AUD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance76 enrolled2 locationsNCT06679062
Recruiting
Phase 2

Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans

Post Traumatic Stress DisorderOpioid-use Disorder
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance120 enrolled2 locationsNCT04360681
Recruiting
Phase 2

Facilitation of Extinction Retention and Reconsolidation Blockade in PTSD

Post Traumatic Stress Disorder
Boston University256 enrolled2 locationsNCT04468360
Recruiting
Phase 2

Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD

Post Traumatic Stress DisorderAlcohol Use Disorder
NYU Langone Health150 enrolled1 locationNCT03667846
Recruiting
Phase 2

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

Post Traumatic Stress Disorder
Stephen Robert Marder40 enrolled2 locationsNCT05790239
Recruiting
Phase 2

MDMA for AUD/PTSD Comorbidity

Post Traumatic Stress DisorderAlcohol Use Disorder
Carolina L Haass-Koffler18 enrolled1 locationNCT05943665
Recruiting
Phase 2

The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects

Depressive DisorderPost Traumatic Stress DisorderSuicidal Ideation+2 more
Yale University30 enrolled1 locationNCT05786066
Recruiting
Phase 2

MDMA-Assisted CBCT for PTSD vs CBCT RCT

Post Traumatic Stress Disorder
Remedy60 enrolled1 locationNCT06044675
Recruiting
Phase 2

Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial

PTSD - Post Traumatic Stress DisorderIntrusive Memories of Traumatic Event(s)
Tel Aviv University60 enrolled1 locationNCT06639061
Completed
Phase 2

Australian 3,4-Methylenedioxymethamphetamine (MDMA)-assisted Psychotherapy Study for the Treatment of Posttraumatic Stress Disorder (PTSD)

Post Traumatic Stress Disorder
Edith Cowan University4 enrolled1 locationACTRN12621001078842