Phase 1 Postoperative Clinical Trials

15 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 115 of 15 trials

Recruiting
Phase 1

Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis

SurgeryPostoperative Blood Loss
Vanderbilt University Medical Center60 enrolled1 locationNCT05774717
Recruiting
Phase 1

The Effect of Oral Gan Shuangbi During the Perinatal Period on the Recovery of Intestinal Function After Cesarean Section in Pregnant Women- A Multicenter, Double-blind, Randomized Controlled Clinical Trial

Postoperative RecoveryMicrobiota
Zhe Li404 enrolled2 locationsNCT06347770
Recruiting
Phase 1

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

Postoperative Pain
Pacira Pharmaceuticals, Inc48 enrolled5 locationsNCT06271265
Recruiting
Phase 1Phase 2

Clinical Study of HRS-2129 for Postoperative Analgesia in Orthopaedics

Postoperative Pain in Orthopaedics
Shandong Suncadia Medicine Co., Ltd.195 enrolled1 locationNCT06780267
Recruiting
Phase 1

Patient Controlled Administration of Liquid Acetaminophen

PainPain, Postoperative
Yale University24 enrolled1 locationNCT06498713
Recruiting
Phase 1Phase 2

Propranolol Treatment for Postoperative Chylothorax

Open-heart surgeryCongenital Heart DiseaseChylothorax+1 more
June Wu50 enrolled1 locationNCT06833320
Recruiting
Phase 1

Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)

Pancreas CancerPeriampullary CancerPancreaticoduodenectomy+1 more
Minia University30 enrolled1 locationNCT07132541
Recruiting
Phase 1Phase 2

Minimally Invasive Esophagectomy Pain Control Trial

Postoperative ComplicationsPostoperative Pain, Acute
Swedish Medical Center30 enrolled1 locationNCT05906134
Recruiting
Phase 1Phase 2

Double-blind Pilot Study on the Effect of Anionic Exposome Enrichment (Biow) on Recovery and Sleep Quality in Postoperative Patients

Postoperative RecoveryInflammatory Response After Surgery
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz150 enrolled1 locationNCT06968000
Recruiting
Phase 1

Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study

Pain After Photorefractive KeratectomyVAS Will be Used to Assess Pain Postoperative
Research Institute of Ophthalmology, Egypt64 enrolled1 locationNCT06752486
Recruiting
Phase 1Phase 2

Amiodarone-Infused CardiaMend Patches for the Prevention of New-Onset POAF in Cardiac Surgery Subjects

Atrial Fibrillation, Postoperative
Helios Cardio Inc.80 enrolled1 locationNCT06730828
Recruiting
Phase 1Phase 2

Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section

Postoperative Ileus
Assiut University90 enrolled1 locationNCT05654649
Completed
Phase 1

An Ascending Dose Study of the Dexmedetomidine Transdermal System in Healthy Subjects

Acute Pain Management in postoperative setting
Clinical Network Services Pty Ltd80 enrolled1 locationACTRN12619000476134
Completed
Phase 1

A healthy volunteer study to test the safety and tolerability of a single dose of the Dexmedetomidine Transdermal System as well as how your body takes it in and disposes and breaks it down.

Acute Pain Management in postoperative setting
Clinical Network Services Pty Ltd36 enrolled1 locationACTRN12618000205235
Completed
Phase 1

Avastin in the prevention of postoperative scarring after glaucoma filtration surgery.

Glaucoma, uncontrolled intraocular eye pressure, trabeculectomy, postoperative intervention, subconjunctival delievery.
Monash Universtity50 enrolled1 locationACTRN12607000318482