Preoperative Clinical Trials

45 recruitingLast updated: June 21, 2026

There are 45 actively recruiting preoperative clinical trials across 18 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 4. Top locations include Ankara, Turkey (Türkiye), Istanbul, Merkez Mahallesi, Turkey (Türkiye), Guangzhou, Guangdong, China. Updated daily from ClinicalTrials.gov.


Preoperative Trials at a Glance

45 actively recruiting trials for preoperative are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 27 trials, with the heaviest enrollment activity in Ankara, Istanbul, and Guangzhou. Lead sponsors running preoperative studies include Ankara City Hospital Bilkent, Istinye University, and Al-Azhar University.

Browse preoperative trials by phase

Treatments under study

About Preoperative Clinical Trials

Looking for clinical trials for Preoperative? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Preoperative trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Preoperative clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting
Not Applicable

Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCT

Preoperative AnxietyFearChildren+1 more
Ankara City Hospital Bilkent69 enrolled1 locationNCT07640230
Recruiting

The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study

Hip ArthroplastyAnxiety PreoperativeFraility
Başakşehir Çam & Sakura City Hospital142 enrolled1 locationNCT07633483
Recruiting
Not Applicable

Auriculotherapy in the Treatment of Pre-Operative Anxiety

Anxiety Preoperative
Jacques E. Chelly60 enrolled1 locationNCT04836936
Recruiting
Not Applicable

Effect of Clinical Hypnosis in Preoperative Anxiety Among Patients Undergoing an Abdominal Surgery.

Postoperative PainPreoperative AnxietyLength of Stay+2 more
HASSAN 1st university48 enrolled3 locationsNCT07370974
Recruiting

COPD Assessment Test Score and Perioperative Risk in COPD

COPDPreoperative Risk Assessment
Erzurum City Hospital120 enrolled1 locationNCT07087626
Recruiting
Not Applicable

Effectiveness of Virtual Reality-enhanced Interventions on Preoperative Anxiety in Adults Undergoing Elective Surgery

Preoperative Anxiety
Sin Lun CHAN270 enrolled1 locationNCT07379450
Recruiting
Not Applicable

Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric Surgery

Preoperative Anxietyemergence agitationPediatric Anesthesia
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital84 enrolled1 locationNCT07565116
Recruiting
Not Applicable

Virtual Reality for Anxiety in Interventional Radiology Procedures

Preoperative Anxiety
Istituto Ortopedico Rizzoli236 enrolled1 locationNCT06745765
Recruiting
Not Applicable

Comparison of Two Relaxation Strategies Between Glasses, Virtual Reality Headset, and Without Relaxation Tool, in the Anxiety Preoperative of Orthopedic Adult Patients

Virtual RealityRelaxationAnxiety Preoperative
Centre Hospitalier Universitaire, Amiens632 enrolled1 locationNCT07557550
Recruiting
Not Applicable

Educational Cartoon to Reduce Preoperative Anxiety in Children (CALM-KIDS)

Pediatric Preoperative Anxiety
Mehmet Burak Eşkin159 enrolled1 locationNCT07495878
Recruiting

Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures

DeliriumPreoperative FastingPostoperative Nausea and Vomiting (PONV)+2 more
University of Giessen1,000 enrolled1 locationNCT07488468
Recruiting

Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study

Myocardial InfarctionSurgery--ComplicationsPreoperative Care
Centre hospitalier de l'Université de Montréal (CHUM)15,000 enrolled16 locationsNCT04973397
Recruiting

Daily Screen Exposure and Preoperative Anxiety in Children Aged 2-5 Years

Preoperative Anxiety
Kanuni Sultan Suleyman Training and Research Hospital275 enrolled1 locationNCT07425405
Recruiting
Not Applicable

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.

Postoperative DeliriumPostoperative Cognitive DysfunctionPreoperative Stress
Heart and Brain Research Group, Germany125 enrolled1 locationNCT05036538
Recruiting
Not Applicable

Preoperative Gamified Breathing Exercise on Anxiety and Delirium in Children.

Postoperative ComplicationsPreoperative Anxiety (Ameliyat Öncesi Anksiyete)Emergence Delirium (Derlenme Deliryumu)+1 more
Bozok University80 enrolled1 locationNCT07408037
Recruiting
Not Applicable

Preoperative Optimization Before Total Hip or Knee Replacement Surgery

PrehabilitationPreoperative Care
Medical University Innsbruck180 enrolled1 locationNCT07394582
Recruiting

Ride-On Toy Car Use During Operating Room Transfer in Preschool Children

Preoperative AnxietyEmergence Delirium in Pediatric Anesthesia
Ankara City Hospital Bilkent96 enrolled1 locationNCT07403747
Recruiting

Personal Versus Hospital-Provided Dolls in Preschool Children

Preoperative AnxietyEmergence Delirium in Pediatric Anesthesia
Ankara City Hospital Bilkent120 enrolled1 locationNCT07403773
Recruiting
Not Applicable

Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery

myocardial injury after non-cardiac surgeryPreoperative PeriodSubmaximal Exercise Performance
Yale University61 enrolled1 locationNCT06474754
Recruiting

Relationship Between Preoperative Anxiety, Postoperative Pain, and Emergence Delirium in Pediatric Surgery

Postoperative PainPreoperative AnxietyUrogenital Diseases+1 more
Aydin Adnan Menderes University60 enrolled1 locationNCT07343388