Phase 3 Prevention Clinical Trials

17 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 117 of 17 trials

Recruiting
Phase 3

Adding Aprepitant to a Multimodal Strategy for the Prevention of Postoperative Nausea and Vomiting in High-risk Outpatient Surgical Patients

PreventionNausea and Vomiting, Postoperative
Centre hospitalier de l'Université de Montréal (CHUM)260 enrolled1 locationNCT07248280
Recruiting
Phase 3

Comparison of an Inhaled Sedation Strategy to an Intravenous Sedation Strategy in Intensive Care Unit Patients Treated With Invasive Mechanical Ventilation

Prevention of Delirium
University Hospital, Brest250 enrolled12 locationsNCT04341350
Recruiting
Phase 3

ENhanced Recovery and ABbreviated LEngth of Anticoagulation for Thromboprophylaxis After Primary Hip Arthroplasty

Hip Arthroplasty, TotalPrevention of Venous Thromboembolism
Prof. Stavros Konstantinides, MD2,932 enrolled6 locationsNCT06611319
Not Yet Recruiting
Phase 2Phase 3

Safety, tolerability and pharmacokinetics of SSTK-101 in healthy volunteers

Prevention of COVID 19
SKYDD Biotechnology Pty Ltd38 enrolled1 locationACTRN12624001064594
Completed
Phase 2Phase 3

Pertaprime: A study to assess the immune response and safety of a new pertussis vaccine (Pertagen®) in healthy young adults.

Pertussis prevention
Telethon Kids Institute102 enrolled1 locationACTRN12619000944134
Completed
Phase 3

Use of Carrageenan spray in the prevention of rhinovirus cold infection

Prevention of rhinovirus cold infection
Julian Crane80 enrolled1 locationACTRN12614000026628
Active
Phase 3

Monitoring of iron status and clinical evaluation of interventions intended to maintain clinically adequate iron status in women who are new blood donors

Prevention of low iron status and iron deficiency in new female blood donors
Dr James M Faed5,100 enrolled1 locationACTRN12612000911897
Completed
Phase 3

The use of tranexamic acid to reduce blood loss during and after cesarean section

Prevention of Postpartum hemorrhage
Faculty of Medicine,Assiut University700 enrolled1 locationACTRN12612000313831
Completed
Phase 2Phase 3

Randomized controlled trial of a new light weight battery operated calf compression device (Venowave) for prevention of venous thrombosis.

venous thrombosis prevention in neurosurgery
Hamilton Health Sciences150 enrolled1 locationACTRN12611000424909
Completed
Phase 3

An international multi-centre study of tamoxifen vs placebo in women at increased risk of breast cancer.

Prevention of Breast cancer
Queen Mary University of London7,000 enrolled1 locationACTRN12610000134022
Recruiting
Phase 3

A randomised controlled trial of Plasmalyte148 with 5% dextrose compared to 0.45% sodium chloride with 5% dextrose for maintenance intravenous fluid therapy in hospitalised children.

Prevention of iatrogenic hyponatraemia
Royal Children's Hospital690 enrolled1 locationACTRN12609000924257
Completed
Phase 3Phase 4

Assessment of microbleeding after prophylaxis with enoxaparin or rivaroxaban against venous thromboembolic disease following hip and knee surgery

Prevention and treatment of venous thromboembolism (VTE); comprising deep vein thrombosis (DVT) and pulmonary embolism (PE) after hip and knee arthroplasty.
Launceston General Hospital1,060 enrolled1 locationACTRN12609000762257
Recruiting
Phase 2Phase 3

Reliability of Intragastric pH probe catheter equipped with temperature sensor for minute to minute monitoring in critically ill patients

stress related mucosal damageprevention of stress related mucosal damage
Tehran university of medical sciences21 enrolled1 locationACTRN12608000197336
Withdrawn
Phase 3

A Phase III Study Comparing Low Dose Cyclosporine, Methotrexate And Prednisone Versus Standard Dose Cyclosporine and Methotrexate As Graft Versus Host Disease Prophylaxis In Myeloblative Allogeneic Stem Cell Transplantation (ALLG BM10 trial). (Incorporating an Open-Label Sub-study Investigating The Use Of Valganciclovir In The Prevention Of Cytomegalovirus Infection In Hematopoietic Stem Cell Transplant Recipients (ML20712))

Prevention Of CytomegalovirusCell Transplant RecipientsProphylaxis In Myeloblative+3 more
Australasian Leukaemia and Lymphoma Group300 enrolled1 locationACTRN12607000347460
Active
Phase 2Phase 3

The efficacy of the LIFE Lifestyle approach to balance and strength training in improving balance and strength in older people: A randomized trial

Falls prevention
The University of Sydney34 enrolled1 locationACTRN12606000013561
Active
Phase 3Phase 4

Vitamin D Intervention To Prevent Falls and Fractures and To Promote Mental Well-Being.

Osteoporosis and fracturesFalls prevention
The University of Melbourne2,300 enrolled1 locationACTRN12605000658617
Completed
Phase 3

Preventing obesity in children via environmental intervention: the APPLE study

Prevention of obesity
University of Otago500 enrolled1 locationACTRN12605000578606