Phase 3 Psychosis Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 3

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease
Karuna Therapeutics, Inc., a Bristol Myers Squibb company500 enrolled154 locationsNCT06126224
Recruiting
Phase 3

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Psychosis Associated With Alzheimer's Disease
Karuna Therapeutics, Inc., a Bristol Myers Squibb company410 enrolled116 locationsNCT05511363
Recruiting
Phase 3

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease
Karuna Therapeutics, Inc., a Bristol Myers Squibb company800 enrolled416 locationsNCT05980949
Recruiting
Phase 3

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

Alzheimer DiseasePsychosis
Bristol-Myers Squibb325 enrolled20 locationsNCT06947941
Recruiting
Phase 3

Efficiency of a Composite Personalised Care on Functional Outcome in Early Psychosis

Psychosis
Centre Hospitalier St Anne500 enrolled13 locationsNCT05796401
Recruiting
Phase 2Phase 3

ACP-204 in Adults With Alzheimer's Disease Psychosis

Alzheimer's Disease Psychosis
ACADIA Pharmaceuticals Inc.1,074 enrolled145 locationsNCT06159673
Recruiting
Phase 3

A Study Evaluating the Efficacy of Xanomeline/Trospium (XT) on Cognitive Impairment After 24 and 52 Weeks of Treatment in Adult Participants With Schizophrenia

Cognitive ImpairmentSchizophrenia; Psychosis
European Group for Research In Schizophrenia171 enrolled16 locationsNCT07084831
Recruiting
Phase 3

Effects of Cannabidiol (CBD) Versus Placebo as an Adjunct to Treatment in Early Psychosis

Early Psychosis
University of California, San Diego120 enrolled2 locationsNCT04411225
Recruiting
Phase 3

Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms.

SchizophreniaApathySchizophrenia; Psychosis
Louisiana State University Health Sciences Center Shreveport80 enrolled1 locationNCT06482554
Not Yet Recruiting
Phase 2Phase 3

Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) effects on perception of illusions, schizotypy and cognition in healthy volunteers

Cannabis use safetySchizophreniaPsychosis
University of Western Australia36 enrolled1 locationACTRN12621000469819
Recruiting
Phase 3

Cannabidiol for At Risk for psychosis Youth

Ultra-High Risk of Psychosis
Orygen405 enrolled1 locationACTRN12621000349842
Completed
Phase 3Phase 4

Seroquel compared to Risperidone in the treatment of psychotic disorders adolescents.

Adolescent psychosis
Dr Harith Swadi60 enrolled1 locationACTRN12605000556640