Phase 3 Pulmonary Hypertension Clinical Trials

11 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 111 of 11 trials

Recruiting
Phase 3

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

Interstitial Lung DiseasePulmonary Hypertension
Insmed Incorporated344 enrolled68 locationsNCT07179380
Recruiting
Phase 3

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

Pulmonary Hypertension Associated With HFpEF
Tenax Therapeutics, Inc.540 enrolled92 locationsNCT07288398
Recruiting
Phase 2Phase 3

Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)

Pulmonary HypertensionRheumatic Valvular Heart Disease
Sindh Institute of Cardiovascular Diseases100 enrolled1 locationNCT07462260
Recruiting
Phase 3

LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF

Pulmonary Hypertension
Tenax Therapeutics, Inc.230 enrolled44 locationsNCT05983250
Recruiting
Phase 3

Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary DiseasePulmonary Hypertension
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT05844462
Recruiting
Phase 3

Safety and Efficacy of FETO in CDH Phase III

Pulmonary HypertensionCongenital Diaphragmatic HerniaPulmonary Hypoplasia
Children's Hospital Medical Center, Cincinnati75 enrolled1 locationNCT07187206
Recruiting
Phase 3

Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis

Acute Coronary SyndromeTuberculosisPulmonary Hypertension (Diagnosis)
National University Hospital, Singapore150 enrolled6 locationsNCT05473520
Recruiting
Phase 3

Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART)

Chronic Thromboembolic Pulmonary Hypertension
Suqiao Yang68 enrolled3 locationsNCT06922240
Recruiting
Phase 3

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure

Heart FailureCardiovascular DiseasesHypertension+5 more
Pulnovo Medical (Wuxi) Co., Ltd.264 enrolled1 locationNCT05824923
Recruiting
Phase 3

Opioids for breathlessness in people with primary hypertension.

Dyspnoea in opioid naive participants with primary pulmonary hypertension.
Flinders University - Department of Palliative and Support Services40 enrolled1 locationACTRN12609000209291
Completed
Phase 3

Safety and Efficacy Study of Ambrisentan in Subjects with Pulmonary Hypertension

Pulmonary Hypertension
Gilead Sciences, Inc.200 enrolled1 locationACTRN12607000170426