Phase 2 Pulmonary Hypertension Clinical Trials
21 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 21 trials
Recruiting
Phase 2
A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489
Pulmonary Hypertension
Pfizer36 enrolled44 locationsNCT07073820
Recruiting
Phase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Cardiovascular DiseasesFibrosisLung Diseases+3 more
Pulmovant, Inc.20 enrolled1 locationNCT07333183
Recruiting
Phase 1Phase 2
Feasibility of Semaglutide in Advanced Lung Disease
ObesityChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+2 more
University of Pennsylvania8 enrolled1 locationNCT05746039
Recruiting
Phase 2
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)
Pulmonary HypertensionHeart Failure With Preserved Ejection Fraction
Tectonic Therapeutic180 enrolled86 locationsNCT06616974
Recruiting
Phase 2Phase 3
Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
Pulmonary HypertensionRheumatic Valvular Heart Disease
Sindh Institute of Cardiovascular Diseases100 enrolled1 locationNCT07462260
Recruiting
Phase 1Phase 2
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital45 enrolled1 locationNCT06947473
Recruiting
Phase 1Phase 2
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH
Refractory Lupus NephritisSystemic SclerosisPrimary Sjogren's Syndrome Combined With Pulmonary Hypertension
Beijing GoBroad Hospital45 enrolled1 locationNCT06947460
Recruiting
Phase 2
129 Xenon Imaging in Patients Treated With Sotatercept
Pulmonary HypertensionPulmonary Arterial Hypertension
Bastiaan Driehuys14 enrolled1 locationNCT06351345
Recruiting
Phase 2
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
Chronic Obstructive Pulmonary DiseaseDyspneaPulmonary Hypertension
VA Office of Research and Development126 enrolled5 locationsNCT05937854
Recruiting
Phase 2
129Xe MRI Cardiopulmonary
DyspneaInterstitial Lung DiseaseAnemia+3 more
Bastiaan Driehuys125 enrolled1 locationNCT06038630
Recruiting
Phase 2
Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension
HFrEF - Heart Failure With Reduced Ejection FractionHFpEF - Heart Failure With Preserved Ejection FractionGroup 2 Pulmonary Hypertension
Salubris Biotherapeutics Inc30 enrolled1 locationNCT07221513
Recruiting
Phase 2
Xenon MRI Pulm Hypertension
Pulmonary HypertensionPulmonary Arterial Hypertension
Bastiaan Driehuys60 enrolled1 locationNCT04991454
Recruiting
Phase 2
Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis
Interstitial Lung DiseasePulmonary HypertensionSystemic Sclerosis+1 more
Paul Szabolcs8 enrolled3 locationsNCT03630211
Recruiting
Phase 2
Study to Evaluate Safety and Efficacy of Mirivadelgat in PH-ILD
Group 3 Pulmonary Hypertension
Foresee Pharmaceuticals Co., Ltd.126 enrolled9 locationsNCT06475781
Recruiting
Phase 2
Feasibility Trial for a Right Ventricular Failure Platform Trial
Pulmonary HypertensionRight Ventricular DysfunctionRight Heart Failure
University of Alberta30 enrolled5 locationsNCT06570473
Recruiting
Phase 2
Bioenergetic Effect of Pioglitazone in CLD-PH
Pulmonary HypertensionPulmonary Hypertension Due to Lung Diseases
Emory University20 enrolled1 locationNCT06336798
Recruiting
Phase 2
A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH)
Pulmonary HypertensionCongenital Diaphragmatic Hernia
University of Utah40 enrolled1 locationNCT05201144
Recruiting
Phase 2
Metformin for Pulmonary Hypertension HFpEF
Heart FailurePulmonary Hypertension
University of California, San Francisco10 enrolled2 locationsNCT03629340
Recruiting
Phase 1Phase 2
Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn
Persistent Pulmonary Hypertension of Newborn
Sohag University40 enrolled1 locationNCT04898114
Recruiting
Phase 2
Inhaled verapamil in patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease (COPD)
Pulmonary hypertension secondary to chronic obstructive pulmonary disease (COPD)
Shahid Beheshti University, M.C.30 enrolled1 locationACTRN12612001239853