Phase 3 Rectal Adenocarcinoma Clinical Trials
6 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–6 of 6 trials
Recruiting
Phase 3
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Rectal AdenocarcinomaColon Adenocarcinoma
Merck Sharp & Dohme LLC477 enrolled161 locationsNCT06997497
Recruiting
Phase 3
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
Stage IV Colorectal Cancer AJCC v8Metastatic Colorectal Adenocarcinoma
Alliance for Clinical Trials in Oncology364 enrolled183 locationsNCT05673148
Recruiting
Phase 3
AK112 and Chemotherapy in First-line Metastatic Colorectal Cancer
Colorectal Adenocarcinoma
Akeso560 enrolled2 locationsNCT06951503
Recruiting
Phase 3
Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal Adenocarcinoma
Adult With Intermediate Low or Mid Rectal Adenocarcinoma
Gustave Roussy, Cancer Campus, Grand Paris212 enrolled11 locationsNCT06402864
Recruiting
Phase 3
Evaluating Novel Therapies in ctDNA Positive GI Cancers
Hepatocellular CarcinomaGastric AdenocarcinomaPancreatic Adenocarcinoma+4 more
Georgetown University20 enrolled3 locationsNCT05482516
Recruiting
Phase 3
PRODIGE 90 - (FFCD 2204) Neoadjuvant Dostarlimab with Short Course Radiotherapy in a Watch-and-wait Strategy for Microsatellite Unstable or Mismatch Repair-deficient Locally Advanced Rectal Cancer Patients
Rectal Adenocarcinoma with Mismatch-repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H)
Centre Hospitalier Universitaire Dijon68 enrolled1 locationNCT06762405