Rectum Cancer Clinical Trials

13 recruiting

Rectum Cancer Trials at a Glance

15 actively recruiting trials for rectum cancer are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Shanghai, Berlin, and Bologna. Lead sponsors running rectum cancer studies include Charite University, Berlin, Germany, Fox Chase Cancer Center, and Cedars-Sinai Medical Center.

Browse rectum cancer trials by phase

Treatments under study

About Rectum Cancer Clinical Trials

Looking for clinical trials for Rectum Cancer? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Rectum Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Rectum Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Not Applicable

Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes

Liver CancerBiliary Tract CancerColon Cancer+76 more
Cedars-Sinai Medical Center360 enrolled1 locationNCT04907643
Recruiting
Not Applicable

Improving Care for Rural Patients With Solid Tumors

Breast CancerCervical CancerLung Cancer+5 more
University of Colorado, Denver320 enrolled14 locationsNCT04916990
Recruiting
Not Applicable

Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery

Rectum Cancer
Technische Universität Dresden12 enrolled1 locationNCT05652361
Recruiting
Not Applicable

Target-specific immunoPET Imaging of Digestive System Carcinoma

MalignancyLiver CancerPancreatic Cancer+12 more
RenJi Hospital400 enrolled1 locationNCT06715839
Recruiting
Phase 1

Adaptive Radiation Boost for Rectal Cancer

Rectum Cancer, Adenocarcinoma
Fox Chase Cancer Center37 enrolled1 locationNCT07221058
Recruiting

ADAR1 Expression Level in Rectal Cancer

Rectum Cancer, Adenocarcinoma
Necmettin Erbakan University50 enrolled1 locationNCT07108348
Recruiting
Not Applicable

Adaptive Symptom Self-Management Immunotherapy Study

Breast CancerLung CancerColon Cancer+2 more
University of Arizona400 enrolled3 locationsNCT05715255
Recruiting

Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer

Rectal CancerRectum CancerCancer of Rectum+4 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology152 enrolled2 locationsNCT03573791
Recruiting
Phase 2

Neoadjuvant FOLFIRINOX and Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer Patients

Rectum Cancer
Menoufia University100 enrolled1 locationNCT06812728
Recruiting
Not Applicable

Image-Guided Surgery In The Treatment Of Rectal Cancer (AR_CRC)

Rectum Cancer
IRCCS Azienda Ospedaliero-Universitaria di Bologna50 enrolled1 locationNCT06805045
Recruiting
Phase 2

SGM-101 in Colorectal Brain Metastases.

Colorectal NeoplasmsGastrointestinal CancerBrain Metastases+10 more
Leiden University Medical Center10 enrolled2 locationsNCT04755920
Recruiting
Not Applicable

End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum

Rectum Cancer
Sohag University20 enrolled1 locationNCT06311279
Recruiting

Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)

Esophageal CancerProstate CancerHead and Neck Cancer+6 more
Charite University, Berlin, Germany649 enrolled1 locationNCT06116019
Recruiting

Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer

Rectum CancerStoma ColostomyFaecal Incontinence+1 more
Shanghai 10th People's Hospital120 enrolled1 locationNCT05245565
Recruiting
Phase 2

Neo-adjuvant Pembrolizumab and Radiotherapy in Localised MSS Rectal Cancer

Rectal CancerRectum Cancer
University Hospital, Geneva25 enrolled1 locationNCT04109755