Recurrent Breast Cancer Clinical Trials

8 recruitingLast updated: June 17, 2026

There are 8 actively recruiting recurrent breast cancer clinical trials across 7 countries. Studies span Phase 2, Phase 1, Not Applicable. Top locations include Barcelona, Spain, Aurora, Colorado, United States, Barakaldo, Spain. Updated daily from ClinicalTrials.gov.


Recurrent Breast Cancer Trials at a Glance

8 actively recruiting trials for recurrent breast cancer are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Phase 2 with 4 trials, with the heaviest enrollment activity in Barcelona, Aurora, and Barakaldo. Lead sponsors running recurrent breast cancer studies include Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Hospital Clinic of Barcelona, and Alpha Tau Medical LTD..

Browse recurrent breast cancer trials by phase

Treatments under study

About Recurrent Breast Cancer Clinical Trials

Looking for clinical trials for Recurrent Breast Cancer? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Recurrent Breast Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Recurrent Breast Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Phase 2

A Trial of Trastuzumab Rezetecan in Unresectable Locally Recurrent/Metastatic Breast Cancer

Unresectable Locally Recurrent Breast CancerUnresectable Locally Metastatic Breast Cancer
Jiangsu HengRui Medicine Co., Ltd.150 enrolled1 locationNCT07497386
Recruiting
Phase 1

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

Triple-Negative Breast CancerMetastatic Breast CancerHER2-positive Breast Cancer+3 more
Royal Marsden NHS Foundation Trust45 enrolled9 locationsNCT04360941
Recruiting
Phase 2

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Metastatic Breast CancerHormone Receptor Positive HER-2 Negative Breast CancerRecurrent Breast Cancer
Puma Biotechnology, Inc.150 enrolled53 locationsNCT06369285
Recruiting
Phase 1

Bortezomib Plus Cisplatin in Recurrent or Metastatic Breast Cancer

Metastatic Breast CancerRecurrent Breast Cancer
Sun Yat-sen University20 enrolled1 locationNCT06900647
Recruiting
Not Applicable

A Study of Diffusing Alpha Radiation Therapy for Patients With Breast Carcinoma in Frail or Elderly Patients.

Breast CancerBreast CarcinomaRecurrent Breast Cancer
Alpha Tau Medical LTD.10 enrolled1 locationNCT06202118
Recruiting
Phase 2

Photo-medicine-Guided Dual Approach for Reoperation of Sentinel Lymph Nodes in Locally Recurrent Breast Cancer Patients

Breast CancerSentinel Lymph Node Biopsy (SLNB)Locally Recurrent Breast Cancer+2 more
National Cancer Center, Korea30 enrolled1 locationNCT06780748
Recruiting

Reoperative Sentinel Lymph Node Biopsy in Patients With Recurrent Ipsilateral Breast Cancer

Recurrent Breast Cancer
Hospital Clinic of Barcelona97 enrolled1 locationNCT06329089
Recruiting
Phase 1Phase 2

A Study of TQB2930 for Injection Monotherapy or Combination Therapy in Patients With Recurrent/Metastatic Breast Cancer

Metastatic Breast CancerRecurrent Breast CancerAdvanced Malignancies
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.154 enrolled2 locationsNCT06202261