Phase 1 Refractory Neuroblastoma Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors
Refractory NeuroblastomaRefractory RhabdomyosarcomaRefractory Solid Tumors+3 more
Theodore Laetsch59 enrolled7 locationsNCT06721689
Recruiting
Phase 1Phase 2
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702
Recruiting
Phase 1Phase 2
Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma
Refractory NeuroblastomaRelapsed Neuroblastoma
Beijing Biotech36 enrolled1 locationNCT07502287
Recruiting
Phase 1
GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma and Metastatic Retinoblastoma
Refractory NeuroblastomaRelapsed Neuroblastoma
Stephan Grupp MD PhD45 enrolled1 locationNCT05650749
Recruiting
Phase 1
PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma
Refractory NeuroblastomaRelapsed Neuroblastoma
Stephan Grupp MD PhD38 enrolled1 locationNCT07007117
Recruiting
Phase 1Phase 2
Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma
Refractory NeuroblastomaRelapsed Neuroblastoma
Roberto Chiarle42 enrolled2 locationsNCT06803875
Recruiting
Phase 1
Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma
NeuroblastomaRefractory OsteosarcomaRefractory Neuroblastoma+2 more
Emory University24 enrolled1 locationNCT05400603
Recruiting
Phase 1
Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma
NeuroblastomaRefractory NeuroblastomaRelapsed Neuroblastoma+1 more
Steven DuBois, MD18 enrolled2 locationsNCT07027748
Recruiting
Phase 1Phase 2
NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab
Refractory NeuroblastomaRelapsed Neuroblastoma
Nationwide Children's Hospital31 enrolled1 locationNCT04211675
Recruiting
Phase 1
TAA06 Injection in the Treatment of Patients With B7-H3-positive Relapsed/ Refractory Neuroblastoma
B7-H3-positive Relapsed/ Refractory Neuroblastoma
PersonGen BioTherapeutics (Suzhou) Co., Ltd.24 enrolled2 locationsNCT05562024