Phase 1 Respiratory Clinical Trials
22 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 22 trials
Recruiting
Phase 1
Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer
Malignant Neoplasms of Respiratory and Intrathoracic OrgansSquamous Cell Carcinoma of the Larynx
M.D. Anderson Cancer Center11 enrolled1 locationNCT03114462
Recruiting
Phase 1Phase 2
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmCOVID-19 Infection+2 more
M.D. Anderson Cancer Center70 enrolled1 locationNCT04565665
Recruiting
Phase 1
Autologous Dendritic Cell Vaccine For Recurrent Respiratory Papillomatosis (RRP) Patients
Recurrent Respiratory Papillomatosis
Mayo Clinic9 enrolled1 locationNCT07317154
Recruiting
Phase 1Phase 2
Mesenchymal Stem Cells (MSCs) and Conditioned Medium Mesenchymal Stem Cells as Adjuvant Therapy for Sepsis
Acute Respiratory Distress Syndrome
PT. Prodia Stem Cell Indonesia15 enrolled1 locationNCT07439848
Recruiting
Phase 1Phase 2
A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Changchun Tuohua Pharmaceutical Co., Ltd.36 enrolled1 locationNCT07413978
Recruiting
Phase 1
A Dose Escalation Study of NanO2 in Patients With Mild Respiratory Distress
Mild Respiratory Distress
NuvOx LLC18 enrolled2 locationsNCT06658535
Recruiting
Phase 1Phase 2
A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection
Cystic Fibrosis LungRespiratory Infections, Recurrent, Chronic
Respirion Pharmaceuticals Pty Ltd72 enrolled22 locationsNCT06016088
Recruiting
Phase 1Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Respiratory Syncytial Virus Infections
Blue Lake Biotechnology Inc.137 enrolled11 locationsNCT05655182
Recruiting
Phase 1
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers
Bacterial InfectionsRespiratory Tract InfectionsUrinary Tract Infections+1 more
Joincare Pharmaceutical Group Industry Co., Ltd66 enrolled1 locationNCT07207291
Recruiting
Phase 1
First-in-human Safety and Immunogenicity Study of SCB-1022 and SCB-1033 in Healthy Older Adults
Respiratory Syncytial Virus VaccinationHuman Metapneumovirus VaccinationParainfluenza Vaccination
Clover Biopharmaceuticals AUS Pty192 enrolled1 locationNCT06984094
Recruiting
Phase 1
Study of the Safety, Tolerability, and Pharmacokinetic Profile of Ascending Doses of Ingavirin Forte, Capsules, Folliwing Single and Subsequent Multiple Oral Administration in Healthy Volunteers
InfluenzaViral Respiratory Infection
Valenta Pharm JSC36 enrolled1 locationNCT06859333
Recruiting
Phase 1Phase 2
Dose-finding for Dobutamine During Transitional Circulation in Very Preterm Infants
Infant, Premature, DiseasesCirculatory and Respiratory Physiological Phenomena
Instituto de Investigación Hospital Universitario La Paz30 enrolled3 locationsNCT06878742
Recruiting
Phase 1
Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists
Opioid Induced Respiratory DepressionChronic Opioid Use
Leiden University Medical Center24 enrolled1 locationNCT05338632
Recruiting
Phase 1
A Study to Describe the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine IN006 in Healthy Adult Aged 18 Years and Above
Respiratory Syncytial Virus Infections
Shenzhen Shenxin Biotechnology Co., Ltd240 enrolled2 locationsNCT06645665
Completed
Phase 1
A DDI Study to Evaluate the Effects of Itraconazole and Fluoxetine on AK0529 in Healthy Volunteers
Respiratory Syncytial Virus Infection
Ark Biosciences Pty Ltd28 enrolled1 locationACTRN12619001413112
Completed
Phase 1
A first in human study to evaluate the safety and immune response to a vaccine for the treatment of a respiratory virus, when administered into the arm in healthy adult participants.
Respiratory Syncytial Virus Infection
Advanced Vaccine Laboratories Pty Ltd60 enrolled1 locationACTRN12618000948291
Completed
Phase 1
Nutrition supplementation and immunity in athletes
Upper respiratory tract illnessGastrointestinal illness
Australian Institute of Sport40 enrolled1 locationACTRN12611000771954
Not Yet Recruiting
Phase 1
Fibrinolytic treatment of acute respiratory failure due to inflammatory lung injury
acute respiratory failure due to inflammatory lung injury
St Vincent's Hospital12 enrolled1 locationACTRN12610000950066
Completed
Phase 1
A Study into High Flow Humidified Nasal Oxygen Therapy (OptiflowTM) and its' Impact on Lung Pressures.
Acute Respiratory Failure
Fisher and Paykel Healthcare Ltd15 enrolled1 locationACTRN12607000372482