Phase 1 Respiratory Clinical Trials
34 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 34 trials
Recruiting
Phase 1
Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions.
InfluenzaAcute Respiratory Viral Infections
Valenta Pharm JSC36 enrolled1 locationNCT07645534
Recruiting
Phase 1Phase 2
Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm in Patients With Acute Respiratory Infection Caused by SARS-Cov-2, Influenza A, Influenza B and Respiratory Syncytial Virus (RSV)
Systemic Inflammatory Response SyndromeSARS CoV-2Respiratory distress syndrome+2 more
PEACHES BIOTECH50 enrolled3 locationsNCT06684379
Recruiting
Phase 1
Pharmacokinetics and Placental Transfer of Caffeine
Apnea of PrematurityPremature BirthBronchopulmonary Dysplasia+2 more
Indiana University30 enrolled1 locationNCT07570121
Recruiting
Phase 1Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Respiratory Syncytial Virus Infections
Blue Lake Biotechnology Inc.137 enrolled15 locationsNCT05655182
Recruiting
Phase 1Phase 2
Clinical Trial of Recombinant RSV Vaccine (CHO Cell) (Adjuvanted) in Chinese Population Aged 18 Years and Older.
Respiratory Syncytial Virus Infections
Ab&B Bio-tech Co., Ltd.JS470 enrolled1 locationNCT07582796
Recruiting
Phase 1
Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS
ARDS (Acute Respiratory Distress Syndrome)
HTIC, Inc24 enrolled2 locationsNCT07449572
Recruiting
Phase 1
Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases
Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1
Macrophage Regulation of Ozone-Induced Lung Inflammation
Respiratory Viral Infection
Robert Tighe, MD100 enrolled1 locationNCT05773001
Recruiting
Phase 1
ENA-001 for Opioid Induced Respiratory Depression
Respiratory Depression
Enalare Therapeutics Inc.36 enrolled3 locationsNCT06967259
Recruiting
Phase 1
Study of Different Formulations of Vaccines Encoding the RSV Monovalent Antigen or the Flu H5 Antigen in Participants 18 to 49 Years of Age
Respiratory Syncytial Virus (RSV)Influenza A(H5N1)
Sanofi570 enrolled6 locationsNCT07516418
Recruiting
Phase 1
A Study of How Ibuzatrelvir is Taken up Into the Blood of Healthy Adults After Taking Different Tablets of Ibuzatrelvir
Upper respiratory tract infectionsrespiratory tract infectionCOVID-19 (SARS-CoV-2) infection+8 more
Pfizer18 enrolled1 locationNCT07552779
Recruiting
Phase 1
Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Laryngeal Cancer
Malignant Neoplasms of Respiratory and Intrathoracic OrgansSquamous Cell Carcinoma of the Larynx
M.D. Anderson Cancer Center11 enrolled1 locationNCT03114462
Recruiting
Phase 1Phase 2
Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia
Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmCOVID-19 Infection+2 more
M.D. Anderson Cancer Center70 enrolled1 locationNCT04565665
Recruiting
Phase 1
Autologous Dendritic Cell Vaccine For Recurrent Respiratory Papillomatosis (RRP) Patients
Recurrent Respiratory Papillomatosis
Mayo Clinic9 enrolled1 locationNCT07317154
Recruiting
Phase 1Phase 2
Mesenchymal Stem Cells (MSCs) and Conditioned Medium Mesenchymal Stem Cells as Adjuvant Therapy for Sepsis
Acute Respiratory Distress Syndrome
PT. Prodia Stem Cell Indonesia15 enrolled1 locationNCT07439848
Recruiting
Phase 1Phase 2
Use of Hyperpolarized Xenon Gas for Lung Imaging in Children and Adults
Respiratory disorders
Children's Hospital Medical Center, Cincinnati300 enrolled1 locationNCT02272049
Recruiting
Phase 1Phase 2
A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Changchun Tuohua Pharmaceutical Co., Ltd.36 enrolled1 locationNCT07413978
Recruiting
Phase 1
A Dose Escalation Study of NanO2 in Patients With Mild Respiratory Distress
Mild Respiratory Distress
NuvOx LLC18 enrolled2 locationsNCT06658535
Recruiting
Phase 1Phase 2
A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection
Pseudomonas aeruginosaCystic Fibrosis LungRespiratory Infections, Recurrent, Chronic
Respirion Pharmaceuticals Pty Ltd72 enrolled22 locationsNCT06016088
Recruiting
Phase 1
Phase I Study of Single/Multiple Ascending Doses of JKN2501 for Injection in Chinese Healthy Volunteers
Bacterial InfectionsRespiratory Tract InfectionsUrinary Tract Infections+1 more
Joincare Pharmaceutical Group Industry Co., Ltd66 enrolled1 locationNCT07207291