Sarcoma Clinical Trials in Boston, Massachusetts
36 recruitingBoston, Massachusetts
Showing 1–20 of 36 trials
Recruiting
Phase 2Phase 3
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Metastatic OsteosarcomaHigh Grade OsteosarcomaLocalized Osteosarcoma+1 more
National Cancer Institute (NCI)1,122 enrolled190 locationsNCT05691478
Recruiting
Phase 1Phase 2
Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)
Relapsed / Refractory Osteosarcoma
Lantheus Medical Imaging55 enrolled2 locationsNCT07357519
Recruiting
Phase 1Phase 2
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
AngiosarcomaLiposarcomaAdipocytic Neoplasm+6 more
St. Jude Children's Research Hospital139 enrolled6 locationsNCT06239272
Recruiting
Phase 1Phase 2
VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors
Solid TumorRhabdomyosarcoma
University of Texas Southwestern Medical Center23 enrolled7 locationsNCT04796012
Recruiting
Phase 1
Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers
Metastatic Endometrial CarcinomaStage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8+8 more
National Cancer Institute (NCI)42 enrolled6 locationsNCT05691504
Recruiting
Not Applicable
Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials
MelanomaBreast Cancer, NOSCNS Primary Tumor, NOS+9 more
Eastern Cooperative Oncology Group400 enrolled347 locationsNCT05108298
Recruiting
Phase 3
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
LeiomyosarcomaRetroperitoneal SarcomaLiposarcoma
European Organisation for Research and Treatment of Cancer - EORTC250 enrolled164 locationsNCT04031677
Recruiting
Phase 1Phase 2
Lurbinectedin in FET-Fused Tumors
Ewing SarcomaPediatric CancerDesmoplastic Small Round Cell Tumor+1 more
Children's Hospital of Philadelphia63 enrolled6 locationsNCT05918640
Recruiting
Phase 1
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Acute Myeloid LeukemiaMyeloid SarcomaAcute Myeloid Leukemia, in Relapse+7 more
Kura Oncology, Inc.420 enrolled44 locationsNCT05735184
Recruiting
Phase 3
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
OsteosarcomaMetastatic Malignant Neoplasm in the LungMetastatic Osteosarcoma
Children's Oncology Group62 enrolled232 locationsNCT05235165
Recruiting
Phase 1Phase 2
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Ovarian CarcinomaColorectal CarcinomaMelanoma+19 more
Children's Oncology Group147 enrolled21 locationsNCT04851119
Recruiting
Phase 1
A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
Advanced Solid TumorsEwing SarcomaHepatocellular Carcinoma (HCC)+1 more
SEED Therapeutics, Inc.171 enrolled6 locationsNCT07197554
Recruiting
Phase 1Phase 2
Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas
SarcomaOsteosarcomaRhabdomyosarcoma+3 more
David S Shulman, MD63 enrolled3 locationsNCT06709495
Recruiting
Phase 1
ACTengine® IMA203 Combined With mRNA-4203
Cutaneous MelanomaSynovial Sarcoma
Immatics US, Inc.15 enrolled4 locationsNCT06946225
Recruiting
Metastatic Leiomyosarcoma Biomarker Protocol
Leiomyosarcoma
University of Michigan Rogel Cancer Center200 enrolled11 locationsNCT05653388
Recruiting
Phase 1Phase 2
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
SarcomaMelanomaNSCLC+3 more
ImmVira Pharma Co. Ltd30 enrolled9 locationsNCT04370587
Recruiting
Phase 2
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders
Langerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more
Carl Allen90 enrolled12 locationsNCT04079179
Recruiting
Phase 1
First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors
SarcomaSolid Tumors
Daiichi Sankyo150 enrolled7 locationsNCT06644755
Recruiting
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
OsteosarcomaRecurrent LymphomaLymphoblastic Lymphoma+4 more
Children's Oncology Group420 enrolled79 locationsNCT01790152
Recruiting
REtroperitoneal SArcoma Registry: an International Prospective Initiative
Retroperitoneal Sarcoma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano2,000 enrolled22 locationsNCT03838718