Sarcoma Clinical Trials in Toronto, Ontario

20 recruitingToronto, Ontario, Canada

Showing 120 of 20 trials

Recruiting
Phase 2Phase 3

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Metastatic OsteosarcomaHigh Grade OsteosarcomaLocalized Osteosarcoma+1 more
National Cancer Institute (NCI)1,122 enrolled190 locationsNCT05691478
Recruiting
Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Metastatic Dedifferentiated LiposarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI)365 enrolled248 locationsNCT06422806
Recruiting
Phase 3

Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer

Stage III Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Eyelid Squamous Cell Carcinoma+17 more
National Cancer Institute (NCI)420 enrolled206 locationsNCT06568172
Recruiting
Phase 3

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

Soft Tissue Sarcoma
Polaris Group300 enrolled31 locationsNCT05712694
Recruiting
Phase 1Phase 2

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702
Recruiting
Phase 1

Actinium Therapy for Late-stage Aggressive Sarcomas

Advanced Soft Tissue Sarcoma
Ratio Therapeutics, Inc.30 enrolled6 locationsNCT07156565
Recruiting
Phase 2

IVIM & OLINK in Sarcoma

Soft Tissue Sarcoma
University Health Network, Toronto145 enrolled1 locationNCT05950594
Recruiting
Phase 2

BAL Fluid Biomarkers in Sarcoma

Soft Tissue Sarcoma (STS)Bronchoalveolar Lavage (BAL)Bronchoalveolar Lavage Fluid
University Health Network, Toronto70 enrolled1 locationNCT06815666
Recruiting
Phase 3

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Embryonal RhabdomyosarcomaFusion-Negative Alveolar RhabdomyosarcomaSpindle Cell/Sclerosing Rhabdomyosarcoma
Children's Oncology Group205 enrolled179 locationsNCT05304585
Recruiting
Phase 3

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Servier Bio-Innovation LLC136 enrolled114 locationsNCT06127407
Recruiting
Phase 1Phase 2

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

Ewing SarcomaRefractory Ewing SarcomaRelapsed Ewing Sarcoma
Jazz Pharmaceuticals60 enrolled15 locationsNCT05734066
Recruiting

PROMIS and Mobility Evaluation in Sarcoma Patients

SarcomaGiant Cell Tumor of Bone
University of Calgary800 enrolled4 locationsNCT07227961
Recruiting
Not Applicable

Evaluating the Use of Educational Videos in Newly Diagnosed Patients in a Medical Oncology Sarcoma Clinic

Sarcoma
Mount Sinai Hospital, Canada100 enrolled1 locationNCT06805773
Recruiting
Phase 2

Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

Breast CancerSarcomaLung Cancer+6 more
British Columbia Cancer Agency200 enrolled2 locationsNCT04273061
Recruiting
Phase 2

A Trial of ABSK043, an Oral PD-L1 Inhibitor, in Patients With Angiogenic Sarcomas

Sarcoma
University Health Network, Toronto20 enrolled1 locationNCT07014137
Recruiting

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

OsteosarcomaRecurrent LymphomaLymphoblastic Lymphoma+4 more
Children's Oncology Group420 enrolled79 locationsNCT01790152
Recruiting
Not Applicable

Digital Peer Navigation for Adolescents and Young Adults With Cancer

Breast CancerSarcomaLymphoma+1 more
University Health Network, Toronto138 enrolled1 locationNCT06193369
Recruiting
Phase 2

EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine Carcinosarcoma

Ovarian CarcinosarcomaUterine Carcinosarcoma
Australia New Zealand Gynaecological Oncology Group30 enrolled6 locationsNCT05619913
Recruiting
Not Applicable

This is a Randomized Study of Early Involvement of Palliative Care Along Side Standard Treatment Versus Standard Treatment Alone in Newly Diagnosed Patients With Advanced or Metastatic Soft Tissue Sarcoma (SARQUALITY)

Sarcoma
Mount Sinai Hospital, Canada136 enrolled1 locationNCT06805669
Recruiting
Not Applicable

Circulating Tumor DNA in Soft Tissue Sarcoma

Soft Tissue Sarcoma
University Health Network, Toronto40 enrolled1 locationNCT03818412