SCD Clinical Trials

6 recruiting

SCD Trials at a Glance

29 actively recruiting trials for scd are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Toronto, Montreal, and Atlanta. Lead sponsors running scd studies include Hebrew University of Jerusalem, Skane University Hospital, and Casa di Cura IGEA.

Browse scd trials by phase

Treatments under study

About SCD Clinical Trials

Looking for clinical trials for SCD? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new SCD trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about SCD clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Not Applicable

Personalized Digital Training for COGnitive FITness in Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Giovanna Zamboni100 enrolled2 locationsNCT07286448
Recruiting
Not Applicable

Increasing Physical Activity Through Social Support and Stress Resilience

Sedentary BehaviorHealthySubjective Cognitive Decline (SCD)+1 more
Arizona State University86 enrolled1 locationNCT06896825
Recruiting
Phase 1Phase 2

FACE Phase II (a Stage II Trial)

MCIMild Behavioral ImpairmentSubjective Cognitive Decline (SCD)
Stanford University80 enrolled1 locationNCT07130669
Recruiting

InRAD Observational Study

Mild Cognitive Impairment (MCI)Alzheimer's Disease(AD)Subjective Cognitive Decline (SCD)+1 more
Stichting International Registry for Alzheimer's Disease and other Dementias Foundation50,000 enrolled1 locationNCT07213700
Recruiting

Sickle Cell Kidney Biorepository

Chronic Kidney DiseaseSickle Cell TraitSickle Cell Disease (SCD)
University of Texas Southwestern Medical Center800 enrolled2 locationsNCT07064174
Recruiting
Not Applicable

Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

Cognitive DeclineAlzheimer DiseaseMild Cognitive Impairment (MCI)+2 more
University of Bern60 enrolled1 locationNCT06669546
Recruiting

The Swedish BioFINDER - Primary Care Study

Alzheimer DiseaseMild Cognitive ImpairmentLewy Body Disease+4 more
Skane University Hospital1,200 enrolled1 locationNCT06120361
Recruiting

The Swedish BioFINDER - Memory Clinic Study

Alzheimer DiseaseMild Cognitive ImpairmentLewy Body Disease+4 more
Skane University Hospital1,200 enrolled1 locationNCT06122415
Recruiting
Not Applicable

Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis

SCDVaso Occlussive Crisis
Imam Abdulrahman Bin Faisal University394 enrolled2 locationsNCT07188766
Recruiting

Lombard Cohort of Brain Health Services

Subjective Cognitive Decline (SCD)Functional Cognitive Disorder
University of Milano Bicocca1,000 enrolled5 locationsNCT07457138
Recruiting
Phase 4

Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease

Sickle Cell Disease (SCD)Vaso-Occlusive Pain Episode in Sickle Cell Disease
University of Pennsylvania65 enrolled2 locationsNCT06665997
Recruiting

The Signature of Alzheimer's Disease in Subjective Cognitive Decline

Subjective Cognitive ImpairmentSubjective Cognitive ConcernsSubjective Cognitive Decline (SCD)+3 more
IRCCS Policlinico S. Donato250 enrolled1 locationNCT07402161
Recruiting

Comprehensive Assessment of Neurodegeneration and Dementia

DementiaMild Cognitive Impairment (MCI)Subjective Cognitive Impairment+7 more
McGill University1,573 enrolled19 locationsNCT03402919
Recruiting
Not Applicable

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Subjective Cognitive Decline (SCD)
Aristotle University Of Thessaloniki128 enrolled1 locationNCT07289061
Recruiting
Not Applicable

Effect of Accelerated Neuromodulation of Anterior Cingulate Cortex to Enhance Cognition in Older Adults With Mild Memory Problems

Mild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Rotman Research Institute at Baycrest30 enrolled1 locationNCT07212504
Recruiting
Not Applicable

A Feasiblity Study of Green Activity Program for People Living With Memory Challenges

Alzheimer DiseaseMild Cognitive ImpairmentSubjective Cognitive Decline (SCD)
Indiana University40 enrolled1 locationNCT06403345
Recruiting
Not Applicable

Exploratory Study on Global Reflexology in Sickle Cell Disease

Sickle Cell Disease (SCD)
Hospices Civils de Lyon30 enrolled1 locationNCT06619197
Recruiting

Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

Sickle Cell Disease (SCD)
University of Rochester480 enrolled37 locationsNCT06941389
Recruiting
Not Applicable

Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline

HealthyAgingMild Cognitive Impairment (MCI)+1 more
National Research Center for Rehabilitation Technical Aids100 enrolled1 locationNCT05014893
Recruiting

CogCoach-Health Randomised Controlled Trial - a lifestyle program targeting brain health in people with cognitive concerns

Mild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
University of New South Wales634 enrolled1 locationACTRN12625000454471