Subjective Cognitive Decline Clinical Trials

16 recruiting

Subjective Cognitive Decline Trials at a Glance

33 actively recruiting trials for subjective cognitive decline are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Toronto, Nanjing, and Jerusalem. Lead sponsors running subjective cognitive decline studies include Hebrew University of Jerusalem, Rotman Research Institute at Baycrest, and The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School.

Browse subjective cognitive decline trials by phase

Treatments under study

About Subjective Cognitive Decline Clinical Trials

Looking for clinical trials for Subjective Cognitive Decline? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Subjective Cognitive Decline trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Subjective Cognitive Decline clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 33 trials

Recruiting
Not Applicable

Personalized Digital Training for COGnitive FITness in Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Giovanna Zamboni100 enrolled2 locationsNCT07286448
Recruiting
Not Applicable

Increasing Physical Activity Through Social Support and Stress Resilience

Sedentary BehaviorHealthySubjective Cognitive Decline (SCD)+1 more
Arizona State University86 enrolled1 locationNCT06896825
Recruiting
Phase 1Phase 2

FACE Phase II (a Stage II Trial)

MCIMild Behavioral ImpairmentSubjective Cognitive Decline (SCD)
Stanford University80 enrolled1 locationNCT07130669
Recruiting

InRAD Observational Study

Mild Cognitive Impairment (MCI)Alzheimer's Disease(AD)Subjective Cognitive Decline (SCD)+1 more
Stichting International Registry for Alzheimer's Disease and other Dementias Foundation50,000 enrolled1 locationNCT07213700
Recruiting
Not Applicable

Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

Cognitive DeclineAlzheimer DiseaseMild Cognitive Impairment (MCI)+2 more
University of Bern60 enrolled1 locationNCT06669546
Recruiting
Not Applicable

Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech

Mild Cognitive ImpairmentSubjective Cognitive DeclineCognitive Function Assessment
Chang Gung Memorial Hospital150 enrolled1 locationNCT07511270
Recruiting

Lombard Cohort of Brain Health Services

Subjective Cognitive Decline (SCD)Functional Cognitive Disorder
University of Milano Bicocca1,000 enrolled5 locationsNCT07457138
Recruiting

The Signature of Alzheimer's Disease in Subjective Cognitive Decline

Subjective Cognitive ImpairmentSubjective Cognitive ConcernsSubjective Cognitive Decline (SCD)+3 more
IRCCS Policlinico S. Donato250 enrolled1 locationNCT07402161
Recruiting

Comprehensive Assessment of Neurodegeneration and Dementia

DementiaMild Cognitive Impairment (MCI)Subjective Cognitive Impairment+7 more
McGill University1,573 enrolled19 locationsNCT03402919
Recruiting
Not Applicable

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Subjective Cognitive Decline (SCD)
Aristotle University Of Thessaloniki128 enrolled1 locationNCT07289061
Recruiting
Not Applicable

Effect of Accelerated Neuromodulation of Anterior Cingulate Cortex to Enhance Cognition in Older Adults With Mild Memory Problems

Mild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Rotman Research Institute at Baycrest30 enrolled1 locationNCT07212504
Recruiting
Not Applicable

dTMS for Subjective Cognitive Decline

Alzheimer DiseaseSubjective Cognitive Decline
Rotman Research Institute at Baycrest30 enrolled1 locationNCT06095063
Recruiting
Not Applicable

A Feasiblity Study of Green Activity Program for People Living With Memory Challenges

Alzheimer DiseaseMild Cognitive ImpairmentSubjective Cognitive Decline (SCD)
Indiana University40 enrolled1 locationNCT06403345
Recruiting
Not Applicable

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

At Risk for AD-dementia, With Subjective Cognitive Decline
University of Minnesota104 enrolled1 locationNCT06340659
Recruiting
Phase 2

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)

HypertensionSubjective Cognitive DeclineCognitively Normal Older Adults+1 more
Rong Zhang180 enrolled1 locationNCT05331144
Recruiting
Not Applicable

Exergame-assisted Simultaneous Motor-cognitive Training for Middle-aged Old Adults in China

Subjective Cognitive Decline
The Hong Kong Polytechnic University30 enrolled1 locationNCT07085663
Recruiting
Early Phase 1

Attentional Mechanisms in SCD

Subjective Cognitive Decline
Vanderbilt University Medical Center80 enrolled1 locationNCT06002477
Recruiting
Not Applicable

Internet-based Mind-Body Training for Brain Health

Subjective Cognitive Decline
Ohio State University60 enrolled1 locationNCT07019402
Recruiting

Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mild Cognitive Impairment of Alzheimer's Disease.

Alzheimer DiseaseMild Cognitive ImpairmentSubjective Cognitive Decline
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation400 enrolled1 locationNCT03851523
Recruiting
Not Applicable

German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)

Alzheimer DiseaseSubjective Cognitive Decline
Ludwig-Maximilians - University of Munich300 enrolled1 locationNCT06711952