Subjective Cognitive Decline Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Subjective Cognitive Decline clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting

Lombard Cohort of Brain Health Services

Alzheimer s DiseaseSubjective Cognitive Decline (SCD)Functional Cognitive Disorder+1 more
University of Milano Bicocca1,000 enrolled5 locationsNCT07457138
Recruiting

The Signature of Alzheimer's Disease in Subjective Cognitive Decline

Subjective Cognitive ImpairmentSubjective Cognitive ConcernsSubjective Cognitive Decline (SCD)+3 more
IRCCS Policlinico S. Donato250 enrolled1 locationNCT07402161
Recruiting

Comprehensive Assessment of Neurodegeneration and Dementia

DementiaMild Cognitive Impairment (MCI)Subjective Cognitive Impairment+7 more
McGill University1,573 enrolled19 locationsNCT03402919
Recruiting
Not Applicable

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Subjective Cognitive Decline (SCD)
Aristotle University Of Thessaloniki128 enrolled1 locationNCT07289061
Recruiting
Not Applicable

dTMS for Subjective Cognitive Decline

Alzheimer DiseaseSubjective Cognitive Decline
Rotman Research Institute at Baycrest30 enrolled1 locationNCT06095063
Recruiting
Not Applicable

A Feasiblity Study of Green Activity Program for People Living With Memory Challenges

Alzheimer DiseaseMild Cognitive ImpairmentSubjective Cognitive Decline (SCD)
Indiana University40 enrolled1 locationNCT06403345
Recruiting
Phase 2

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)

HypertensionSubjective Cognitive DeclineCognitively Normal Older Adults+1 more
Rong Zhang180 enrolled1 locationNCT05331144
Recruiting

Longitudinal Study for the Characterization of the Phases of Subjective Perception of Cognitive Decline and Mild Cognitive Impairment of Alzheimer's Disease.

Alzheimer DiseaseMild Cognitive ImpairmentSubjective Cognitive Decline
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation400 enrolled1 locationNCT03851523
Recruiting
Not Applicable

German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)

Alzheimer DiseaseSubjective Cognitive Decline
Ludwig-Maximilians - University of Munich300 enrolled1 locationNCT06711952
Recruiting

HOme-based Brain Monitoring With a GARment-EEG to Study Cognitive Decline in the Aging Population

DementiaDementia, VascularDementia, Mixed+3 more
Bitbrain500 enrolled1 locationNCT06993207
Recruiting
Not Applicable

Developing a Peer Support Intervention for Depression in SCD

Subjective Cognitive DeclineDepression in Old Age
Massachusetts General Hospital30 enrolled1 locationNCT06358404
Recruiting
Not Applicable

Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

Cognitive DeclineAlzheimer DiseaseMild Cognitive Impairment (MCI)+2 more
University of Bern60 enrolled1 locationNCT06669546
Recruiting

Korean Joint Registry for Alzheimer's Treatment and Diagnostics (JOY-ALZ)

DementiaAlzheimer DiseaseMild Cognitive Impairment+1 more
Ewha Womans University Mokdong Hospital4,000 enrolled3 locationsNCT06889818
Recruiting

China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)

DementiaCognitive DysfunctionType 2 Diabetes+2 more
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School10,000 enrolled1 locationNCT06650969
Recruiting

Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers

Mild Cognitive ImpairmentAlzheimer Disease, Late OnsetSubjective Cognitive Decline
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School1,000 enrolled1 locationNCT06561906
Recruiting

The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)

Alzheimer DiseaseMild Cognitive ImpairmentSubjective Cognitive Decline+4 more
The First Affiliated Hospital with Nanjing Medical University209 enrolled1 locationNCT06335836