MCI Clinical Trials

15 recruiting

MCI Trials at a Glance

84 actively recruiting trials for mci are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 47 trials, with the heaviest enrollment activity in Toronto, Phoenix, and Boston. Lead sponsors running mci studies include St. Joseph's Hospital and Medical Center, Phoenix, University of California, San Francisco, and Centre for Addiction and Mental Health.

Browse mci trials by phase

Treatments under study

About MCI Clinical Trials

Looking for clinical trials for MCI? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new MCI trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about MCI clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 84 trials

Recruiting
Not Applicable

Non-invasive Stimulation of Deep Brain Structures to Modulate Working Memory

Mild Cognitive Impairment (MCI)Older Adults (60 - 85 Years Old)
Masaryk University70 enrolled1 locationNCT07560904
Recruiting
Not Applicable

Personalized Digital Training for COGnitive FITness in Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Giovanna Zamboni100 enrolled2 locationsNCT07286448
Recruiting

Genetic Studies of Early-onset Dementia

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Memory Loss+1 more
Columbia University1,000 enrolled1 locationNCT04906863
Recruiting
Phase 3

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Urinary Bladder NeoplasmsImmune Checkpoint InhibitorsMethotrexate+4 more
AstraZeneca150 enrolled59 locationsNCT06960577
Recruiting
Phase 1Phase 2

FACE Phase II (a Stage II Trial)

MCIMild Behavioral ImpairmentSubjective Cognitive Decline (SCD)
Stanford University80 enrolled1 locationNCT07130669
Recruiting
Not Applicable

A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia

DementiaAlzheimer DiseaseAlzheimer Disease, Early Onset+1 more
University of Campania Luigi Vanvitelli50 enrolled1 locationNCT06668610
Recruiting

InRAD Observational Study

Mild Cognitive Impairment (MCI)Alzheimer's Disease(AD)Subjective Cognitive Decline (SCD)+1 more
Stichting International Registry for Alzheimer's Disease and other Dementias Foundation50,000 enrolled1 locationNCT07213700
Recruiting
Phase 1Phase 2

Biomarker-based Trial of NPC-1 for Alzheimer's Pathology

Alzheimer DiseaseMild Cognitive Impairment (MCI)Subjective Cognitive Complaints (SCCs)
Massachusetts General Hospital40 enrolled1 locationNCT07236190
Recruiting
Not Applicable

Brain Stimulation and Cognitive Training for MCI

Mild Neurocognitive DisorderCognitive DysfunctionMild Cognitive Impairment (MCI)+2 more
Medical University of South Carolina50 enrolled1 locationNCT07526740
Recruiting
Not Applicable

Feasibility Study of 'SuperBrain BOOM' for Mild Cognitive Impairment Patients

Mild Cognitive Impairment (MCI)
Ajou University School of Medicine45 enrolled4 locationsNCT07101380
Recruiting
Not Applicable

TACS to Engage Theta-Gamma Coupling and Enhance Working Memory in Patients With MCI (tACS-MCI)

Mild Cognitive Impairment (MCI)
Centre for Addiction and Mental Health20 enrolled1 locationNCT06783283
Recruiting
Not Applicable

Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

Cognitive DeclineAlzheimer DiseaseMild Cognitive Impairment (MCI)+2 more
University of Bern60 enrolled1 locationNCT06669546
Recruiting
Not Applicable

Exercises for Rehabilitation of COgnition and Lifestyle Enhancement in Patients With Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)
Casa di Cura IGEA40 enrolled2 locationsNCT07517380
Recruiting
Not Applicable

BID WM Digital Intervention in Aging

AgingMild Cognitive Impairment (MCI)Working Memory+1 more
University of California, San Francisco150 enrolled1 locationNCT06918704
Recruiting

Predicting Pre-dementia

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Alzheimer Disease (AD)+1 more
Prevention Research Consortium Corp.100 enrolled1 locationNCT07516119
Recruiting
Not Applicable

Early-Stage Partner in Care Living Alone Plus

DementiaAlzheimer DiseaseMild Cognitive Impairment (MCI)
Arizona State University70 enrolled1 locationNCT06962111
Recruiting
Not Applicable

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

BPSDDementiaMCI+2 more
Indiana University60 enrolled1 locationNCT07499570
Recruiting
Not Applicable

Compared Reversed US-Guided Dorsal Penile Nerve Block (RUSDPNB) With DPNB in Circumcisions for Pediatric Patients

UltrasoundCircumcisionOpioid Consumption+1 more
Centre Hospitalier Universitaire Vaudois216 enrolled1 locationNCT06706375
Recruiting

Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort

Depression - Major Depressive DisorderChronic PainMild Cognitive Impairment (MCI)+1 more
Korea University180 enrolled1 locationNCT07485387
Recruiting

Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)Major Depressive Disorder, RemittedHealthy Controls Group - Age and Sex-matched
Centre for Addiction and Mental Health150 enrolled3 locationsNCT06780917