MCI Clinical Trials

7 recruiting

Frequently Asked Questions

Common questions about MCI clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 44 trials

Recruiting

Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment

Mild Cognitive Impairment (MCI)Major Depressive Disorder, RemittedHealthy Controls Group - Age and Sex-matched
Centre for Addiction and Mental Health150 enrolled3 locationsNCT06780917
Recruiting
Phase 2

Repurposing Siponimod for Alzheimer's Disease

Alzheimer DiseaseCognitive Impairment, MildMild Alzheimer Disease+1 more
St. Joseph's Hospital and Medical Center, Phoenix105 enrolled1 locationNCT06639282
Recruiting
Not Applicable

Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

Mild Cognitive Impairment (MCI) AmnesticLewy Body Disease With Mild Cognitive ImpairmentParkinson's Disease With Mild Cognitive Impairment
Masaryk University70 enrolled1 locationNCT07449117
Recruiting
Phase 3

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

Urinary Bladder NeoplasmsImmune Checkpoint InhibitorsMethotrexate+4 more
AstraZeneca150 enrolled59 locationsNCT06960577
Recruiting
Not Applicable

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

Mild Cognitive Impairment (MCI)Parkinsons Disease (PD)Healthy Adult
University of Colorado, Denver80 enrolled1 locationNCT07424365
Recruiting
Phase 3

Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function

Subjects With Mild Cognitive Impairment (MCI) of AD, Alzheimer's Disease (AD) Dementia
JYAMS PET Research & Development Limited316 enrolled2 locationsNCT07422857
Recruiting
Not Applicable

Validation of a Digital Intervention to Rehabilitate Cognitive Resources

Mild Cognitive Impairment (MCI)Dementia Alzheimer TypeSubjective Memory Complaint
Fondazione Don Carlo Gnocchi Onlus102 enrolled1 locationNCT07064226
Recruiting

The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients

MCI
Beni-Suef University300 enrolled1 locationNCT07244770
Recruiting

Neurocognitive Assessment Platform 4 Alzheimer

Alzheimer DiseaseMCIAMCI - Amnestic Mild Cognitive Impairment+1 more
IRCCS San Raffaele100 enrolled1 locationNCT07272811
Recruiting

Comprehensive Assessment of Neurodegeneration and Dementia

DementiaMild Cognitive Impairment (MCI)Subjective Cognitive Impairment+7 more
McGill University1,573 enrolled19 locationsNCT03402919
Recruiting
Not Applicable

VIrtual Reality Induced Pain and anxiEty Relief in Outpatient UROlogical Procedures

PainStressAnxiety+4 more
Istituto Oncologico Veneto IRCCS56 enrolled1 locationNCT07338292
Recruiting
Not Applicable

Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Subjective Cognitive Decline (SCD)
Aristotle University Of Thessaloniki128 enrolled1 locationNCT07289061
Recruiting
Not Applicable

Early Stage of Alzheimer's and Parkinson's Diseases, HearIng Relevance (SAPHIR)

Healthy ParticipantsMild Cognitive Impairment (MCI) AmnesticParkinson Disease (PD)
Cilcare SAS309 enrolled4 locationsNCT07083089
Recruiting
Not Applicable

Infrared Light for Memory Loss in Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Unity Health Toronto60 enrolled1 locationNCT06618807
Recruiting

Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative Diseases

Alzheimer DiseaseParkinson DiseaseFTD+3 more
Ospedale Policlinico San Martino1,200 enrolled1 locationNCT07235111
Recruiting
Phase 1

Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study

Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)
National University Hospital, Singapore48 enrolled1 locationNCT07210528
Recruiting
Not Applicable

Technological Devices in Circumcision

Circumcision AdultCircumcision, MaleCircumcision
Adiyaman University50 enrolled1 locationNCT06793722
Recruiting
Phase 2

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

Sleep DisturbanceAMCI - Amnestic Mild Cognitive Impairment
Johns Hopkins University100 enrolled1 locationNCT05282550
Recruiting
Not Applicable

TACS to Engage Theta-Gamma Coupling and Enhance Working Memory in Patients With MCI (tACS-MCI)

Mild Cognitive Impairment (MCI)
Centre for Addiction and Mental Health20 enrolled1 locationNCT06783283
Recruiting

A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population

Mild Cognitive Impairment (MCI)Mild Alzheimer Disease
Indivi AG55 enrolled1 locationNCT07174869