Phase 1 SCI Clinical Trials
19 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–19 of 19 trials
Recruiting
Phase 1Phase 2
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
X-linked Severe Combined Immunodeficiency (XSCID)
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled1 locationNCT01306019
Recruiting
Phase 1
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
Lumbosacral RadiculopathySciaticaSciatic Radiculopathy+3 more
Consano Bio24 enrolled3 locationsNCT07264270
Recruiting
Phase 1Phase 2
Intraperitoneal SK-NK Cell Injection for Advanced Ovarian Cancer With Massive Ascites
AscitesOvarian Neoplasms Malignant
Cancer Institute and Hospital, Chinese Academy of Medical Sciences29 enrolled1 locationNCT07435701
Recruiting
Phase 1
A Study of GensSci098 in Subjects With Graves' Disease
SafetyGraves DiseaseTolerability+1 more
Changchun GeneScience Pharmaceutical Co., Ltd.24 enrolled1 locationNCT07286656
Recruiting
Phase 1
A Study of GenSci098 in Subjects With Active Thyroid Eye Disease
SafetyTolerabilityGenSci098+1 more
Changchun GeneScience Pharmaceutical Co., Ltd.76 enrolled1 locationNCT06569758
Recruiting
Phase 1
Lateral Plantar Artery Embolization For Plantar Fasciitis
Plantar Fasciitis, Chronic
Joint & Vascular Institute10 enrolled1 locationNCT07395128
Recruiting
Phase 1Phase 2
A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC
Esophageal Squamous Cell CarcinomaNeoadjuvantIvonescimab
Tang-Du Hospital45 enrolled1 locationNCT07385001
Recruiting
Phase 1Phase 2
A First-in-Human, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of Gene Therapy With TTX-381 for the Ocular Manifestations Associated With Neuronal Ceroid Lipofuscinosis Type 2 (CLN2) Disease
Neuronal Ceroid Lipofuscinosis Type 2
Tern Therapeutics, LLC16 enrolled2 locationsNCT05791864
Recruiting
Phase 1Phase 2
Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids for Gastric Cancer Malignant Ascites
Ascites, MalignantCancer of Stomach, Adenocarcinoma
Qilu Hospital of Shandong University24 enrolled1 locationNCT06759064
Recruiting
Phase 1Phase 2
SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection
SCID, X-Linked
Shenzhen Geno-Immune Medical Institute10 enrolled2 locationsNCT03217617
Recruiting
Phase 1
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics
Cirrhosis, LiverLiver FibrosisAscites Hepatic
PharmaIN74 enrolled9 locationsNCT05490888
Recruiting
Phase 1Phase 2
Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury
Acute Spinal Cord Injury (SCI)
Technophage, SA28 enrolled2 locationsNCT06677229
Recruiting
Phase 1Phase 2
Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI
Neuropathic PainSCI - Spinal Cord Injury
University of Miami20 enrolled1 locationNCT05630235
Recruiting
Phase 1Phase 2
Double Dose 4-AP on Functional Recovery After Spinal Cord Injury
SCI - Spinal Cord Injury
Shirley Ryan AbilityLab27 enrolled1 locationNCT06853015
Recruiting
Phase 1
NG004 in Spinal Cord Injury Patients
Central Nervous System DiseasesNervous System DiseasesTrauma, Nervous System+4 more
NovaGo Therapeutics AG21 enrolled6 locationsNCT06817577
Recruiting
Phase 1
The Neurobiological Effect of 5-HT2AR Modulation
Basic Science
Gitte Moos Knudsen200 enrolled1 locationNCT03289949
Withdrawn
Phase 1
Understanding the profile of midazolam administered using the NasoSURF device to healthy volunteers
Conscious Sedation
AFT Pharmaceuticals Ltd10 enrolled1 locationACTRN12621001427864
Completed
Phase 1
PsiConnect: Brain Connectivity and Context under Psilocybin
Neural mechanisms of psilocybin induced altered-states of consciousness
Monash University60 enrolled1 locationACTRN12621001375842
Terminated
Phase 1
A phase Ia study of MRC202 in patients with malignant ascites caused by cancer.
Malignant ascites (hydoperitoneum) associated with cancer
MRC Biotech Pty Ltd12 enrolled1 locationACTRN12607000078459