Sclerosis Clinical Trials in Philadelphia, Pennsylvania

31 recruitingPhiladelphia, Pennsylvania

Showing 120 of 31 trials

Recruiting
Phase 1

A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

Systemic Lupus Erythematosus (SLE)Systemic Sclerosis (SSc)Lupus Nephritis+2 more
Fate Therapeutics244 enrolled18 locationsNCT06308978
Recruiting
Phase 1

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmRheumatoid Arthritis+11 more
National Cancer Institute (NCI)300 enrolled52 locationsNCT03816345
Recruiting
Phase 4

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)123 enrolled12 locationsNCT05285891
Recruiting
Not Applicable

taVNS for FRNS in Children

Nephrotic Syndrome in ChildrenFocal Segmental GlomerulosclerosisMinimal Change Disease
Northwell Health30 enrolled2 locationsNCT05588063
Recruiting
Phase 3

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis
Sanofi1,600 enrolled384 locationsNCT06141473
Recruiting
Phase 2

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

Multiple Sclerosis Spasticity
Celgene200 enrolled53 locationsNCT06782490
Recruiting

Transformative Research in Diabetic Nephropathy

Diabetic NephropathiesDiabetic Glomerulosclerosis
University of Pennsylvania400 enrolled17 locationsNCT02986984
Recruiting
Phase 3

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

Multiple Sclerosis
Sanofi900 enrolled338 locationsNCT06141486
Recruiting
Not Applicable

Central Vein Sign in Multiple Sclerosis Extension Study

Multiple Sclerosis
The Cleveland Clinic40 enrolled3 locationsNCT07424027
Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

Primary Progressive Aphasia(PPA)Frontotemporal Degeneration(FTD)Familial Frontotemporal Lobar Degeneration (fFTLD)+2 more
University of Pennsylvania1,000 enrolled1 locationNCT04715399
Recruiting

PREVENT ALL ALS Study

Amyotrophic Lateral Sclerosis
St. Joseph's Hospital and Medical Center, Phoenix600 enrolled32 locationsNCT06581861
Recruiting
Phase 2Phase 3

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

Scleroderma, SystemicSystemic Sclerosis Associated Interstitial Lung Disease
GlaxoSmithKline300 enrolled131 locationsNCT05878717
Recruiting

ASSESS ALL ALS Study

Amyotrophic Lateral Sclerosis
St. Joseph's Hospital and Medical Center, Phoenix2,000 enrolled32 locationsNCT06578195
Recruiting
Phase 3

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

Relapsing Multiple SclerosisRelapsing Remitting Multiple SclerosisSecondary Progressive Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)156 enrolled22 locationsNCT04047628
Recruiting
Phase 2

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

Alport SyndromeFocal Segmental GlomerulosclerosisImmunoglobulin A Nephropathy+2 more
Travere Therapeutics, Inc.67 enrolled47 locationsNCT05003986
Recruiting
Not Applicable

Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study

Amyotrophic Lateral Sclerosis
University of Pennsylvania20 enrolled1 locationNCT06119087
Recruiting
Phase 2

A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

Secondary Progressive Multiple Sclerosis
Tiziana Life Sciences LTD54 enrolled7 locationsNCT06292923
Recruiting

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Amyotrophic Lateral SclerosisCorticobasal Degeneration (CBD)Progressive Supranuclear Palsy (PSP)+11 more
Mayo Clinic2,100 enrolled27 locationsNCT04363684
Recruiting

TSC Biosample Repository and Natural History Database

LymphangioleiomyomatosisTuberous Sclerosis
National Tuberous Sclerosis Association5,000 enrolled24 locationsNCT05676099
Recruiting

Obesity and Pediatric Multiple Sclerosis

Multiple Sclerosis
University of Virginia116 enrolled2 locationsNCT04593082