Sjögren Clinical Trials

3 recruiting

Frequently Asked Questions

Common questions about Sjögren clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Phase 1

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease

Sjogren's SyndromeSjogren DiseaseSjögren
Cullinan Therapeutics Inc.36 enrolled10 locationsNCT07041099
Recruiting
Phase 1Phase 2

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
Novartis Pharmaceuticals27 enrolled10 locationsNCT07048197
Recruiting
Early Phase 1

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

Rheumatoid ArthritisSystemic Lupus ErythematosusAnti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis+3 more
Changhai Hospital60 enrolled1 locationNCT07246096
Recruiting
Phase 3

A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)

Sjögren's Syndrome
Amgen844 enrolled144 locationsNCT06747949
Recruiting
Phase 2

A PHASE II PROSPECTIVE RANDOMIZED DOUBLE-MASKED CONTROLLED STUDY ASSESSING THE SAFETY & EFFICACY OF RHPRG4 (450 µG/ML RECOMBINANT HUMAN PROTEOGLYCAN 4) COMPARED TO VEHICLE FOR THE TREATMENT OF SJÖGREN'S RELATED DRY EYE DISEASE

Sjögren's Syndrome
Lubris Bio Pty Ltd80 enrolled6 locationsNCT07118241
Recruiting
Phase 1

DR-0201 in Subjects With Autoimmune Diseases

SclerodermaSLEDermatomyositis+9 more
Dren Bio36 enrolled10 locationsNCT06647069
Recruiting
Phase 1

Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases

Relapsed/Refractory Systemic Lupus ErythematosusRelapsed/Refractory Systemic SclerosisRelapsed/Refractory Idiopathic Inflammatory Myopathies+3 more
Beijing Boren Hospital12 enrolled1 locationNCT07361094
Recruiting

The Myelin Disorders Biorepository Project

AdrenoleukodystrophyCockayne SyndromeRefsum Disease+63 more
Children's Hospital of Philadelphia12,000 enrolled23 locationsNCT03047369
Recruiting
Phase 1

A Study to Evaluate the Effects of ASP5502 in Healthy Adults and Adults With Primary Sjögren's Syndrome

Healthy VolunteersSjögren's Syndrome
Astellas Pharma Global Development, Inc.132 enrolled1 locationNCT06544642
Recruiting
Phase 2

Laser Acupuncture on Dry Eye and Sjögren's Syndrome-related Dry Eye Symptoms (LADESJS)

Dry Eye Syndrome (DES)Laser AcupunctureSjögren's Syndrome (SS)
Taipei Veterans General Hospital, Taiwan140 enrolled1 locationNCT06780293
Recruiting

Autoreactive Anti-Ro/SSA IgE To Determine Primary SjögRen's Syndrome's Disease Activity

Primary Sjögren's Syndrome
Centre Hospitalier Universitaire de Saint Etienne185 enrolled8 locationsNCT03003572
Recruiting

Dental and Periodontal Status of Patients With Sjögren's Syndrome.

Sjögren Syndrome
Assistance Publique - Hôpitaux de Paris100 enrolled1 locationNCT04848870
Recruiting
Phase 4

The Efficacy and Safety of Iguratimod (IGU) in the Treatment of Primary Sjögren's Syndrome

Primary Sjögren's Syndrome
Second Affiliated Hospital, School of Medicine, Zhejiang University78 enrolled1 locationNCT04981145
Recruiting

ROLE of PLATELETS in the PATHOPHYSIOLOGY of SYSTEMIC LUPUS

Rheumatoid ArthritisSystemic Lupus ErythematosusSystemic Scleroderma Meeting+3 more
University Hospital, Strasbourg, France450 enrolled1 locationNCT06593041
Recruiting

Prevalence of Pre-clinical Sjögren Disease and Other Immune Disturbances in Subjects With Autoimmune Thyroiditis Disease

SjögrenAutoimmune Thyroid Disease
IRCCS Burlo Garofolo150 enrolled2 locationsNCT06324578