Phase 4 SMA Clinical Trials

29 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 29 trials

Recruiting
Phase 4

Comparison of Outcomes of Management of Bowel Obstruction

Adhesive Small Bowel Obstruction
University of Washington550 enrolled4 locationsNCT07084441
Recruiting
Phase 4

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hepatocellular CarcinomaMetastatic Lung Non-Small Cell Carcinoma+18 more
OHSU Knight Cancer Institute160 enrolled1 locationNCT07405086
Recruiting
Phase 4

Early Lumbar Drainage Plus Intrathecal Urokinase in Severe Aneurysmal Subarachnoid Hemorrhage (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage
Second Affiliated Hospital of Nanchang University424 enrolled25 locationsNCT06284642
Recruiting
Phase 4

PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly With Thoracic Malignancies

Lung CancerNon-small Cell Lung Cancer
GFPC Investigation500 enrolled41 locationsNCT06646471
Recruiting
Phase 4

Dabrafenib and/or Trametinib Rollover Study

MelanomaNon-small Cell Lung CancerSolid Tumor+2 more
Novartis Pharmaceuticals100 enrolled28 locationsNCT03340506
Recruiting
Phase 4

A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Lymphocytic LeukemiaLymphoma, Small Lymphocytic
Eli Lilly and Company150 enrolled53 locationsNCT07218341
Recruiting
Phase 4

Anesthesia and Non-small Cell Lung Cancer Recurrence

SurgeryNon-small Cell Lung CancerAnesthesia
Samsung Medical Center5,384 enrolled1 locationNCT06330038
Recruiting
Phase 4

Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With External Ventricular Drainage

Subarachnoid Hemorrhage, Aneurysmal
Aaron Cook20 enrolled1 locationNCT06119061
Recruiting
Phase 4

Postoperative Radiotherapy for Postoperative N2 Metastases of NSCLC in the Immunotherapy Era (Phase II)

Non-small Cell Lung Cancer
Fujian Cancer Hospital60 enrolled1 locationNCT07320105
Recruiting
Phase 4

Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related Arrhythmias

Persistent Atrial FibrillationParoxysmal Atrial FibrillationLong-standing Persistent Atrial Fibrillation
Vivek Reddy275 enrolled5 locationsNCT06765356
Recruiting
Phase 3Phase 4

Comparative Efficacy of 70% Tricholoacetic acid versus cryotherapy in treatment of Xanthelasma palpebrum

Xanthelasma palpaberum
Pakistan naval ship Shifa hospital, Karachi60 enrolled1 locationACTRN12625001236482
Recruiting
Phase 4

Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan

Extensive-stage Small-cell Lung Cancer
Pharmacosmos A/S302 enrolled1 locationNCT05874401
Recruiting
Phase 4

HighCycle Study: Acetazolamide, High Altitude and Plasma Volume

WomenHigh Altitude EffectsHigh Altitude Hypoxia+2 more
Centre d'Expertise sur l'Altitude EXALT270 enrolled1 locationNCT07118462
Recruiting
Phase 4

Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage

HeadacheAneurysmal Subarachnoid Hemorrhage (aSAH)
Wright State University20 enrolled1 locationNCT07116408
Recruiting
Phase 4

Chemoradiotherapy With Surgery Followed by Consolidation Durvalumab

Non-Small Cell Lung Cancer (Stage III)
Idris Bahce38 enrolled1 locationNCT06908070
Recruiting
Phase 4

China Stroke Primary Prevention Trial 2 for Participants With H-type Hypertension and MTHFR 677 CC/CT Genotype (CSPPT2-CC/CT)

HypertensionMTHFR 677 CC or CT GenotypeElevated Plasma Homocysteine (Hcy≥10µmol/L)+1 more
Shenzhen Ausa Pharmed Co.,Ltd32,000 enrolled20 locationsNCT04974138
Recruiting
Phase 4

Improving Osimertinib Exposure and Cost-effectiveness Using Pharmacokinetic Boosting With Cobicistat

Non-small Cell Lung Cancer
Maastricht University Medical Center60 enrolled1 locationNCT05748093
Recruiting
Phase 4

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Traumatic Brain InjuryIntracerebral HemorrhageSubarachnoid Hemorrhage, Aneurysmal
Rigshospitalet, Denmark400 enrolled1 locationNCT05095857
Recruiting
Phase 4

Study on the Therapeutic Effect of Irinotecan Liposomes in Small Cell Lung Cancer

Small Cell Lung Cancer
Tang-Du Hospital24 enrolled1 locationNCT06467786
Recruiting
Phase 4

Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels

Lung CancerCarcinoma, Non-Small Cell LungDrug Monitoring+2 more
University Medical Center Groningen196 enrolled8 locationsNCT05525338