Phase 1 Solid Tumor Cancer Clinical Trials
23 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 23 trials
Recruiting
Phase 1Phase 2
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
ParagangliomaPheochromocytomaSolid Tumor Cancer+19 more
Fundación de investigación HM25 enrolled1 locationNCT06607692
Recruiting
Phase 1
Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
Advanced Solid Tumor Cancer
Calico Life Sciences LLC248 enrolled30 locationsNCT04777994
Recruiting
Phase 1Phase 2
BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)
Urothelial CancerLocally AdvancedSolid Tumor Cancer+1 more
Avenzo Therapeutics, Inc.355 enrolled10 locationsNCT07193511
Recruiting
Phase 1
QLS5212 for Participants With Advanced Solid Tumors
Solid Tumor Cancer
Qilu Pharmaceutical Co., Ltd.100 enrolled1 locationNCT07467629
Recruiting
Phase 1Phase 2
Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors
Advanced Solid Tumor Cancer
BioNTech SE533 enrolled5 locationsNCT07455734
Recruiting
Phase 1Phase 2
AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Lung CancersUrothelial CancerLocally Advanced+5 more
Avenzo Therapeutics, Inc.480 enrolled18 locationsNCT07038343
Recruiting
Phase 1
Phase I, Open-labeled, Dose-escalation, Dose-expansion Study Evaluating the Safety, Tolerance, Pharmacokinetics, and Activity of IUAb190708 in Patients With Advanced or Recurrent Solid Tumors
Solid Tumor CancerSolid Tumor Cancer Treatment With Immunotherapy
Jun Zhou90 enrolled6 locationsNCT07584954
Recruiting
Phase 1
Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors
Breast CancerOvarian CancerCancer+4 more
Conjupro Biotherapeutics, Inc.386 enrolled5 locationsNCT07424547
Recruiting
Phase 1
A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combinations in Advanced Solid Tumors
Advanced Solid Tumor Cancer
HC Biopharma Inc.331 enrolled1 locationNCT07477743
Recruiting
Phase 1Phase 2
IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors
Solid Tumor CancerPDAC
InxMed (Shanghai) Co., Ltd.92 enrolled14 locationsNCT07441174
Recruiting
Phase 1
A First in Human Study of PLT012 in Participants With Solid Tumor Cancers
Solid Tumor CancerAdvanced Malignant Solid Tumor
Pilatus Biosciences Inc36 enrolled2 locationsNCT07337525
Recruiting
Phase 1
X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma
Advanced Solid Tumor Cancer
Immunolight, LLC52 enrolled4 locationsNCT04389281
Recruiting
Phase 1
A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer
Advanced Solid Tumor Cancer
HC Biopharma Inc.328 enrolled1 locationNCT07381829
Recruiting
Phase 1Phase 2
Study of GV20-0251 in Participants With Solid Tumor Malignancies
MelanomaNon-small Cell Lung CancerSolid Tumor Cancer+6 more
GV20 Therapeutics350 enrolled3 locationsNCT07070518
Recruiting
Phase 1
A Phase I Study of WTX212A Monotherapy or in Combination With Radiotherapy in Patients With Advanced Solid Tumors
CancerSolid Tumor Cancer
Sun Yat-sen University12 enrolled2 locationsNCT07269899
Recruiting
Phase 1Phase 2
A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors
Non-small Cell Lung CancerSolid Tumor Cancer
Shanghai Henlius Biotech105 enrolled3 locationsNCT06848699
Recruiting
Phase 1Phase 2
Exploratory Study of Super DC Cell Injection in Preventing Recurrence After Radical Surgery for Tumors
Solid Tumor Cancer
Shanghai Cell Therapy Group Co.,Ltd12 enrolled1 locationNCT07146672
Recruiting
Phase 1
Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors
Advanced Solid Tumor Cancer
Peking University10 enrolled2 locationsNCT07139067
Recruiting
Phase 1
Imatinib and Trametinib for KRAS-mutated Solid Tumor
Solid Tumor Cancer
China Medical University Hospital10 enrolled1 locationNCT06962254
Recruiting
Phase 1
Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of MPD-1 in Patients With Advanced Solid Tumor
CancerSolid Tumor CancerBiomarkers
Pharosgen Co.,Ltd24 enrolled1 locationNCT06944457