Phase 1 Solid Tumor Cancer Clinical Trials
21 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 21 trials
Recruiting
Phase 1Phase 2
BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001)
Urothelial CancerLocally AdvancedSolid Tumor Cancer+1 more
Avenzo Therapeutics, Inc.355 enrolled9 locationsNCT07193511
Recruiting
Phase 1Phase 2
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
Solid Tumor CancerHigh Risk NeuroblastomaMedulloblastoma
Fundación de investigación HM25 enrolled1 locationNCT06607692
Recruiting
Phase 1
Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors
Breast CancerOvarian CancerCancer+4 more
Conjupro Biotherapeutics, Inc.386 enrolled5 locationsNCT07424547
Recruiting
Phase 1Phase 2
Early-phase Trial to Assess the Safety and Preliminary Efficacy of BNT3214 in Adults With Advanced Solid Tumors
Advanced Solid Tumor Cancer
BioNTech SE533 enrolled4 locationsNCT07455734
Recruiting
Phase 1
A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combinations in Advanced Solid Tumors
Advanced Solid Tumor Cancer
HC Biopharma Inc.331 enrolled1 locationNCT07477743
Recruiting
Phase 1Phase 2
IN10018 in Combination With RNK08954 for the Treatment of KRASG12D Mutation-Positive Locally Advanced or Metastatic Solid Tumors
Solid Tumor CancerPDAC
InxMed (Shanghai) Co., Ltd.92 enrolled14 locationsNCT07441174
Recruiting
Phase 1Phase 2
AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Lung CancersLocally AdvancedSolid Tumor Cancer+2 more
Avenzo Therapeutics, Inc.430 enrolled16 locationsNCT07038343
Recruiting
Phase 1
A First in Human Study of PLT012 in Participants With Solid Tumor Cancers
Solid Tumor CancerAdvanced Malignant Solid Tumor
Pilatus Biosciences Inc36 enrolled2 locationsNCT07337525
Recruiting
Phase 1
X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma
Advanced Solid Tumor Cancer
Immunolight, LLC52 enrolled4 locationsNCT04389281
Recruiting
Phase 1
A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combined With Chemotherapy in Lung Cancer
Advanced Solid Tumor Cancer
HC Biopharma Inc.328 enrolled1 locationNCT07381829
Recruiting
Phase 1
Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors
Advanced Solid Tumor Cancer
Calico Life Sciences LLC248 enrolled30 locationsNCT04777994
Recruiting
Phase 1Phase 2
Study of GV20-0251 in Participants With Solid Tumor Malignancies
Solid Tumor CancerAdult Refractory CancerEndometrial Carcinoma (EC)+2 more
GV20 Therapeutics350 enrolled3 locationsNCT07070518
Recruiting
Phase 1
A Phase I Study of WTX212A Monotherapy or in Combination With Radiotherapy in Patients With Advanced Solid Tumors
CancerSolid Tumor Cancer
Sun Yat-sen University12 enrolled2 locationsNCT07269899
Recruiting
Phase 1Phase 2
A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors
Solid Tumor Cancer
Shanghai Henlius Biotech105 enrolled3 locationsNCT06848699
Recruiting
Phase 1Phase 2
Exploratory Study of Super DC Cell Injection in Preventing Recurrence After Radical Surgery for Tumors
Solid Tumor Cancer
Shanghai Cell Therapy Group Co.,Ltd12 enrolled1 locationNCT07146672
Recruiting
Phase 1
Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors
Advanced Solid Tumor Cancer
Peking University10 enrolled2 locationsNCT07139067
Recruiting
Phase 1
Imatinib and Trametinib for KRAS-mutated Solid Tumor
Solid Tumor Cancer
China Medical University Hospital10 enrolled1 locationNCT06962254
Recruiting
Phase 1
Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of MPD-1 in Patients With Advanced Solid Tumor
CancerSolid Tumor CancerBiomarkers
Pharosgen Co.,Ltd24 enrolled1 locationNCT06944457
Recruiting
Phase 1Phase 2
AD1208 in Subjects With Any Progressive, Locally Advanced or Metastatic Solid Tumors
Solid TumorSolid Tumor, AdultSolid Tumor Cancer+4 more
Avelos Therapeutics Inc.36 enrolled3 locationsNCT06911333
Recruiting
Phase 1
A Phase I Study of LXP1788 Injection with Advanced Solid Tumors.
Pancreas CancerSolid Tumor CancerHCC - Hepatocellular Carcinoma+6 more
LaunXP Biomedical Co., Ltd.24 enrolled2 locationsNCT06883539