Phase 1 Solid Tumors Clinical Trials

10 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 110 of 10 trials

Recruiting
Phase 1

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Solid Tumors
Incyte Corporation710 enrolled34 locationsNCT06179160
Recruiting
Phase 1Phase 2

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

Gastric CancerSolid Tumors
EMD Serono Research & Development Institute, Inc.250 enrolled81 locationsNCT06710132
Recruiting
Phase 1

Study of INCB123667 in Subjects With Advanced Solid Tumors

Solid Tumors
Incyte Corporation604 enrolled46 locationsNCT05238922
Recruiting
Phase 1Phase 2

JAB-2485 Activity in Adult Patients With Advanced Solid Tumors

Solid TumorsER+ Breast Cancer
Jacobio Pharmaceuticals Co., Ltd.102 enrolled8 locationsNCT05490472
Recruiting
Phase 1

A Study of Lutetium [177Lu]-BL-ARC001 in Patients With Locally Advanced or Metastatic Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors

Breast CancerLung CancerSolid Tumors+1 more
Sichuan Baili Pharmaceutical Co., Ltd.22 enrolled1 locationNCT07274852
Recruiting
Phase 1Phase 2

Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration

Solid Tumors
ORIC Pharmaceuticals350 enrolled42 locationsNCT05315700
Recruiting
Phase 1Phase 2

Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors

Hepatocellular CarcinomaSolid TumorsNon-small Cell Lung Cancer+1 more
3D Medicines (Sichuan) Co., Ltd.170 enrolled23 locationsNCT05024214
Recruiting
Phase 1

Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors

Solid Tumors
Hansoh BioMedical R&D Company780 enrolled1 locationNCT06621563
Recruiting
Phase 1Phase 2

A Study of DC05F01 in Chinese Patients with Recurrent/Refractory Ovarian Cancer and Other Advanced Solid Tumors

Ovarian CancerSolid TumorsSmall Cell Lung Cancer
Heronova Pharmaceuticals60 enrolled2 locationsNCT06873555
Recruiting
Phase 1Phase 2

CTS2190 Phase I /II Clinical Study in Patients

Pancreatic CancerSolid TumorsNon-small Cell Lung Cancer
CytosinLab Therapeutics Co., Ltd.224 enrolled2 locationsNCT06224387