Early Phase 1 Solid Tumors Clinical Trials

20 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 120 of 20 trials

Recruiting
Early Phase 1

NK521 in the Treatment of Malignant Ascites Associated With Advanced Solid Tumors

Advanced Solid Tumors
Base Therapeutics (Shanghai) Co., Ltd.18 enrolled1 locationNCT07561437
Recruiting
Early Phase 1

Clinical Study on the Efficacy and Safety of CAR-DC in the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Peking University Shenzhen Hospital10 enrolled1 locationNCT07504445
Recruiting
Early Phase 1

Exploring the Clinical Value of RT01-89Zr PET Imaging in Solid Tumors

Solid Tumors
Nanolattix Biotechnology Co., Ltd.10 enrolled1 locationNCT07505069
Recruiting
Early Phase 1

A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX37 in Advanced/Metastatic Solid Tumors

NSCLCAdvanced/Metastatic Solid Tumors
Shanghai Henlius Biotech254 enrolled2 locationsNCT07274813
Recruiting
Early Phase 1

A Single-Arm, Open-Label Clinical Study GK01 Cell Injection in Subjects With Advanced Solid Tumors.

Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD10 enrolled1 locationNCT07414316
Recruiting
Early Phase 1

HEAT Trial (HER2 Antibody Therapy With Lutetium-177)

Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1

A Clinical Study of GK02 in Malignant Ascites

Malignant Ascites Caused by Advanced Solid Tumors
Beijing Geekgene Technology Co., LTD9 enrolled1 locationNCT07378436
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences36 enrolled1 locationNCT07349160
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Advanced Solid Tumors
Shanghai Juncell Therapeutics20 enrolled1 locationNCT04967833
Recruiting
Early Phase 1

Safety and Efficacy of Metabolically Armed Tumor-lnfiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors

Advanced Solid Tumors
Anhui Provincial Hospital36 enrolled1 locationNCT07106814
Recruiting
Early Phase 1

HF50 in HER-2 Positive and Low-expression Advanced Solid Tumors

Advanced Solid Tumors
HighField Biopharmaceuticals Corporation10 enrolled1 locationNCT06822998
Recruiting
Early Phase 1

Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Solid Tumors

Pancreatic NeoplasmsOther Solid Tumors
Ruijin Hospital56 enrolled1 locationNCT06577532
Recruiting
Early Phase 1

AMT-676 in Patients With Advanced Solid Tumors

Advanced Solid Tumors
Multitude Therapeutics Inc.24 enrolled13 locationsNCT06400485
Recruiting
Early Phase 1

Personalized KSX01-TCRT in Patients With Advanced Solid Tumors

Refractory Solid TumorsRelapsed Solid Tumors
Cancer Institute and Hospital, Chinese Academy of Medical Sciences12 enrolled1 locationNCT06150365
Recruiting
Early Phase 1

Safety and Preliminary Efficacy of Anti-CDH17 CAR-T Cell Therapy in Patients with CDH17-positive Advanced Solid Tumors

CDH17-positive Advanced Solid Tumors
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China30 enrolled1 locationNCT06820424
Recruiting
Early Phase 1

A Dose Escalation and Dose Expansion Trial of WTX212A in the Treatment of Patients with Advanced Malignant Tumors

Unresectable or Metastatic Advanced Solid Tumors
Zhejiang University44 enrolled1 locationNCT06026605
Recruiting
Early Phase 1

Evaluate the Safety and Tolerability of JCXH-212 Monotherapy and Combined With Toripalimab in the Treatment of Malignant Solid Tumors

Malignant Solid Tumors
Peking University Cancer Hospital & Institute24 enrolled1 locationNCT05579275
Recruiting
Early Phase 1

Study to Evaluate Maximum Tolerated Dose of Oral CB-03-10 With Dose Expansion Phase, in Advanced Solid Tumors

Advanced Refractory Solid TumorsSubjects Considered Likely to Respond to CB-03-10
Cosmo Technologies Ltd90 enrolled6 locationsNCT03863145
Recruiting
Early Phase 1

KSX01-TCRT Injection Project in Solid Tumors

Refractory Solid TumorsRelapsed Solid TumorsTCR-T Cells
TCRx Therapeutics Co.Ltd50 enrolled1 locationNCT05811975
Recruiting
Early Phase 1

KSH01-TCRT Solid Tumors

Refractory Solid TumorsRelapsed Solid TumorsTCR-T Cells
TCRx Therapeutics Co.Ltd50 enrolled1 locationNCT05539833