Phase 1 SON Clinical Trials
75 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 75 trials
Recruiting
Phase 1
Relative Bioavailability Study of HNC364 Injectable Suspension
Parkinson's Disease (PD)
Guangzhou Henovcom Bioscience Co. Ltd.30 enrolled1 locationNCT06798519
Recruiting
Phase 1Phase 2
This Clinical Trial is Designed to Evaluate the Safety, Tolerability, Feasibility and Preliminary Efficacy of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in Patients With Parkinson's Disease.
Parkinson Disease
iRegene Therapeutics Co., Ltd.5 enrolled1 locationNCT07102342
Recruiting
Phase 1
Safety and Feasibility of Bilateral Striatal Transplantation of DopaCell in Parkinson's Disease
Parkinson Disease (PD)
Royan Institute10 enrolled1 locationNCT07572071
Recruiting
Phase 1
Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.
Parkinsons Disease (PD)
Pravat Mandal12 enrolled1 locationNCT07064005
Recruiting
Phase 1Phase 2
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
Colorectal, CancerStenosisFibrosis, Liver+4 more
Massachusetts General Hospital80 enrolled1 locationNCT05692024
Recruiting
Phase 1
Efficacy and Safety of Autologous Peptide-induced Active Immunity in AML Maintenance Therapy
Acute Myeloid LeukemiaMaintenance TherapyPersonalized Active Immunotherapy
Fujian Medical University Union Hospital90 enrolled1 locationNCT07551037
Recruiting
Phase 1Phase 2
The University of Alabama at Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy
Parkinson Disease
University of Alabama at Birmingham205 enrolled1 locationNCT03457493
Recruiting
Phase 1
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
DementiaALSMild Cognitive Impairment+2 more
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting
Phase 1
SAD Study in Patients With Parkinson's Disease and Motor Fluctuations
PARKINSON DISEASE (Disorder)Advanced Parkinson's Disease
Serina Therapeutics40 enrolled6 locationsNCT07422675
Recruiting
Phase 1Phase 2
rTMS to Improve Cognition in Parkinson's
Mild Cognitive ImpairmentParkinson's Disease
VA Office of Research and Development56 enrolled2 locationsNCT03836950
Recruiting
Phase 1
Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients
Parkinson DiseaseParkinson's Disease
Innopeutics Corporation6 enrolled1 locationNCT07371338
Recruiting
Phase 1
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Parkinson Disease
Eli Lilly and Company127 enrolled14 locationsNCT06809400
Recruiting
Phase 1
A Study to Test How BI 3031185 is Tolerated by People With Borderline Personality Disorder or Attention-deficit/Hyperactivity Disorder
Attention Deficit Hyperactivity DisorderBorderline Personality Disorder
Boehringer Ingelheim96 enrolled12 locationsNCT07001475
Recruiting
Phase 1
First-in-Human Single and Multiple Dose of HL-400
Parkinson Disease
Highlightll Pharmaceutical (USA) LLC86 enrolled1 locationNCT06997484
Recruiting
Phase 1
A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease
Parkinson Disease
University of Michigan5 enrolled1 locationNCT07543861
Recruiting
Phase 1
A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy
Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
iRegene Therapeutics Co., Ltd.9 enrolled1 locationNCT07289477
Recruiting
Phase 1
First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)
Parkinsons Disease
Regeneron Pharmaceuticals46 enrolled2 locationsNCT07216066
Recruiting
Phase 1
Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies
Multiple System AtrophyParkinsons Disease
Craig van Horne, MD, PhD7 enrolled1 locationNCT06683365
Recruiting
Phase 1
Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons
Parkinson Disease
Jeffrey S. Schweitzer, MD, PhD8 enrolled1 locationNCT06687837
Recruiting
Phase 1
Research Into the Safety of a New Agent (VT-5006) in People With and Without Parkinson's Disease
Healthy Volunteers (HV)Parkinson's Disease (PD)
Vertero Therapeutics84 enrolled1 locationNCT07310264