Phase 1 SON Clinical Trials
82 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 82 trials
Recruiting
Phase 1Phase 2
Personalized Neoantigen Peptide Vaccines for Solid Tumors
Solid TumorsAdvanced CancerRecurrent Cancer+2 more
Seqker Biosciences, Inc.10 enrolled1 locationNCT07002203
Recruiting
Phase 1
A Phase I Study in Healthy Volunteers and Parkinson's Disease (PD) Patients.
Early-stage Parkinson’s diseaseParkinson's Disease (PD)Mild to Moderate Parkinson's Disease
Mission Therapeutics106 enrolled18 locationsNCT07630545
Recruiting
Phase 1
Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults
Influenza PreventionSeasonal Influenza
National Institute of Allergy and Infectious Diseases (NIAID)45 enrolled1 locationNCT06863142
Recruiting
Phase 1
Clinical Trials of IBI3035 in Healthy Subjects
Healthy Person
Innovent Biologics (Suzhou) Co. Ltd.144 enrolled1 locationNCT07591519
Recruiting
Phase 1Phase 2
Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)
Parkinson's Disease (PD)
EicOsis Human Health Inc.18 enrolled1 locationNCT07142044
Recruiting
Phase 1
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
DementiaALSMild Cognitive Impairment+2 more
National Institute of Mental Health (NIMH)184 enrolled1 locationNCT04396873
Recruiting
Phase 1
A Study to Evaluate Satety, Tolerability, Biodistribution, Radiation Dosimetry, and Pharmacokinetics of SST001 in Healthy Volunteers, Patients With PD and Patients With MSA
Parkinson's Disease (PD)Multiple System Atrophy (MSA)
Synusight Biotech (Shanghai) Co., Ltd.30 enrolled2 locationsNCT07604116
Recruiting
Phase 1
Safety and Efficacy of Autologous iNSC-DAP in the Treatment of Parkinson's Disease
Parkinson's Disease
Xuanwu Hospital, Beijing6 enrolled1 locationNCT05901818
Recruiting
Phase 1
A Clinical Study to Evaluate the Safety of MF1, a New Treatment for Parkinson's Disease-related Disorders (MF1 Study)
Healthy Adult MalePARKINSON DISEASE (Disorder)
University of Shizuoka58 enrolled1 locationNCT07666022
Recruiting
Phase 1
Safety and Feasibility of Bilateral Striatal Transplantation of DopaCell in Parkinson's Disease
Parkinson Disease (PD)
Royan Institute6 enrolled3 locationsNCT07572071
Recruiting
Phase 1
Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease
PARKINSON DISEASE (Disorder)
University of Alabama at Birmingham24 enrolled1 locationNCT07557706
Recruiting
Phase 1
A Study to Test How BI 3031185 is Tolerated by People With Borderline Personality Disorder or Attention-deficit/Hyperactivity Disorder
Attention Deficit Hyperactivity DisorderBorderline Personality Disorder
Boehringer Ingelheim68 enrolled7 locationsNCT07001475
Recruiting
Phase 1
SAD Study in Patients With Parkinson's Disease and Motor Fluctuations
PARKINSON DISEASE (Disorder)Advanced Parkinson's Disease
Serina Therapeutics40 enrolled6 locationsNCT07422675
Recruiting
Phase 1Phase 2
A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder
Borderline personality disorder (BPD)
Mclean Hospital20 enrolled1 locationNCT07460947
Recruiting
Phase 1
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
Parkinson's Disease
Prevail Therapeutics124 enrolled4 locationsNCT06565195
Recruiting
Phase 1
Relative Bioavailability Study of HNC364 Injectable Suspension
Parkinson's Disease (PD)
Guangzhou Henovcom Bioscience Co. Ltd.30 enrolled1 locationNCT06798519
Recruiting
Phase 1Phase 2
This Clinical Trial is Designed to Evaluate the Safety, Tolerability, Feasibility and Preliminary Efficacy of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in Patients With Parkinson's Disease.
Parkinson Disease
iRegene Therapeutics Co., Ltd.5 enrolled1 locationNCT07102342
Recruiting
Phase 1
Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.
Parkinsons Disease (PD)
Pravat Mandal12 enrolled1 locationNCT07064005
Recruiting
Phase 1Phase 2
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
Colorectal, CancerStenosisFibrosis, Liver+4 more
Massachusetts General Hospital80 enrolled1 locationNCT05692024
Recruiting
Phase 1
Efficacy and Safety of Autologous Peptide-induced Active Immunity in AML Maintenance Therapy
Acute Myeloid LeukemiaMaintenance TherapyPersonalized Active Immunotherapy
Fujian Medical University Union Hospital90 enrolled1 locationNCT07551037