Phase 3 Spinal Clinical Trials
28 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 28 trials
Recruiting
Phase 3
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)
Muscular Atrophy, Spinal
Biogen30 enrolled2 locationsNCT07221669
Recruiting
Phase 2Phase 3
Tranexamic Acid to Reduce Blood Loss in Spine Surgery
Spinal DeformitySpinal Injuries
Columbia University252 enrolled4 locationsNCT02314988
Recruiting
Phase 3
Tranexamic Acid in Adult Spinal Deformity Surgery
Blood Loss, SurgicalSpinal DeformityDegenerative Lumbar Spinal Stenosis
Hospital for Special Surgery, New York100 enrolled1 locationNCT03553186
Recruiting
Phase 3
Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression
Opioid UsePain, PostoperativePain, Back+1 more
Hospital for Special Surgery, New York150 enrolled1 locationNCT05058287
Recruiting
Phase 3
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam
Spinal Muscular Atrophy
Biogen90 enrolled1 locationNCT07444476
Recruiting
Phase 2Phase 3
Transcutaneous Spinal Cord Stimulation for Upper Extremity Function
StrokeSpinal Cord Injuries
University of Alberta30 enrolled2 locationsNCT06596369
Recruiting
Phase 3
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
Spinal Muscular Atrophy (SMA)
Novartis Pharmaceuticals175 enrolled32 locationsNCT05335876
Recruiting
Phase 2Phase 3
Epidural Stimulation and Resistance Training After SCI
Spinal Cord Injuries
United States Department of Defense20 enrolled1 locationNCT04782947
Recruiting
Phase 3
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Nerve BlockAnesthesia, SpinalArthroplasties, Knee Replacement+1 more
University of Toronto50 enrolled1 locationNCT07050277
Recruiting
Phase 3
Real World Clinical Effectiveness & Safety of Vesemnogene Lantuparvovec for Spinal Muscular Atrophy (SMA) in Low-middle Income Countries (LMIC).
Spinal Muscular Atrophy (SMA)
Lantu Biopharma15 enrolled1 locationNCT07265232
Recruiting
Phase 2Phase 3
IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study
Surgery--ComplicationsIron-deficiencySpinal Fusion+4 more
Columbia University120 enrolled1 locationNCT07217873
Recruiting
Phase 3
Home-based Cycling for People With Lumbar Spinal Stenosis
Symptomatic Lumbar Spinal Stenosis
Assistance Publique - Hôpitaux de Paris302 enrolled1 locationNCT04075539
Recruiting
Phase 2Phase 3
Effects of 5HTP on the Injured Human Spinal Cord
Spinal Cord Injuries
University of Alberta30 enrolled2 locationsNCT04520178
Recruiting
Phase 3
Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases
Spinal Metastases
Stanford University274 enrolled1 locationNCT06173401
Recruiting
Phase 3
Safety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular Atrophy (SMA) - Phase III
SMA - Spinal Muscular Atrophy
GeneCradle Inc50 enrolled7 locationsNCT06971094
Recruiting
Phase 2Phase 3
Non-Invasive Neuromodulation for Upper Extremity Function in Spinal Cord Injury: A Crossover Trial
Spinal Cord Injury Cervical
University of Alberta10 enrolled1 locationNCT06903416
Recruiting
Phase 3
A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain
Postoperative PainPostoperative DeliriumSpinal Fusion
University of California, San Francisco278 enrolled1 locationNCT05010148
Recruiting
Phase 3
Effect of Ketamine on Intraoperative Motor Evoked Potentials
Spinal StenosisSpine FusionSpine Tumor
University of California, San Francisco20 enrolled1 locationNCT06140927
Recruiting
Phase 2Phase 3
Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy
Spinal and Bulbar Muscular Atrophy
Masahisa Katsuno68 enrolled5 locationsNCT06862596
Recruiting
Phase 3
Use of Iv Tramadol and Ketamine for Prevention of Post Spinal Anesthesia Shivering
Shivering, Spinal Anesthesia
Liaquat National Hospital & Medical College250 enrolled3 locationsNCT06722742