Phase 4 Spinal Clinical Trials
41 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 41 trials
Recruiting
Phase 4
Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
Lumbar Spinal StenosisSciatica Acute
Primus Pharmaceuticals50 enrolled24 locationsNCT06157177
Recruiting
Phase 4
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy
Muscular Atrophy, Spinal
Hoffmann-La Roche28 enrolled19 locationsNCT05861999
Recruiting
Phase 4
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy
Muscular Atrophy, Spinal
Hoffmann-La Roche28 enrolled16 locationsNCT05861986
Recruiting
Phase 4
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
Type 2 DiabetesSpinal Cord Injuries
Marzieh Salehi50 enrolled2 locationsNCT06706284
Recruiting
Phase 4
CraniSeal Post Approval Study
Leak, Cerebrospinal Fluid
Pramand LLC224 enrolled8 locationsNCT06406790
Recruiting
Phase 4
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Anesthesia, SpinalAnalgesics, OpioidAdverse Anesthesia Outcome+1 more
Medical University of Silesia120 enrolled3 locationsNCT06878014
Recruiting
Phase 4
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Lumbar RadiculopathyDegenerative Disc DiseaseLumbar Spinal Stenosis+7 more
John O'Toole125 enrolled1 locationNCT05029726
Recruiting
Phase 4
Post-Operative Thoracolumosacral Orthosis for PJK
Proximal Junctional KyphosisAdult Spinal Deformity SurgeryThoracolumbosacral Orthosis
Hospital for Special Surgery, New York84 enrolled6 locationsNCT06491030
Recruiting
Phase 4
Patient Preference and Long-term Outcomes in Persistent Spinal Pain Syndrome: A Prospective Study Comparing Spinal Cord Stimulation to Intrathecal Drug Delivery.
Persistent Spinal Pain Syndrome
University Hospitals Cleveland Medical Center36 enrolled1 locationNCT07091123
Recruiting
Phase 4
Hemodynamics During Cesarean Delivery Under Spinal Anesthesia With Norepinephrine Versus Ephedrine
cesarean deliverySpinal anesthesia for cesarean section
Mansoura University200 enrolled1 locationNCT07322419
Recruiting
Phase 4
Intrathecal Dexmedetomidine vs Epinephrine
Cesarean SectionAnesthesia, Spinal
Icahn School of Medicine at Mount Sinai62 enrolled1 locationNCT06418308
Recruiting
Phase 4
Comparative Analysis of Intraoperative Effect Dexmedetomidine and Fentanyl as an Adjuvant to Heavy Bupivacaine in Spinal Anaesthesia in Lower Limb Orthopedic Surgeries to Evaluate the Hemodynamic Stability and Onset and Duration of Motor Block of Using Intrathecal Dexmedetomidine and Fentanyl
Spinal Anesthesia Duration
Nashwa Ahmed40 enrolled1 locationNCT07078201
Recruiting
Phase 4
Ketorolac Effects on Post-operative Pain and Lumbar Fusion
Lumbar Spinal Fusion
University of Maryland St. Joseph Medical Center140 enrolled1 locationNCT06513208
Recruiting
Phase 4
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
Spinal surgeryPost Operative Pain
The Cleveland Clinic120 enrolled1 locationNCT07222072
Recruiting
Phase 4
Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities
Multiple SclerosisSpinal Cord InjuryCentreal Neurological Condition+1 more
Oxford University Hospitals NHS Trust50 enrolled1 locationNCT07303582
Recruiting
Phase 4
Feasibility of Early Gabapentin as an Intervention for Neurorecovery
Spinal Cord Injuries
MetroHealth Medical Center42 enrolled1 locationNCT05302999
Recruiting
Phase 4
Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
Sleep ApneaSpinal Cord Injury
John D. Dingell VA Medical Center100 enrolled1 locationNCT02922894
Recruiting
Phase 4
Comparison of Perineural Dexamethasone Versus Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Lumbar Spine Surgery: A Randomized, Double-blind, Controlled Trial
Spine DiseaseSpinal Diseases
Poznan University of Medical Sciences150 enrolled1 locationNCT07180940
Recruiting
Phase 4
Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF
SurgeryDisc DegenerationDisc Disease+2 more
Potsawat Surabotsopon60 enrolled1 locationNCT06367855
Recruiting
Phase 4
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Post Operative AnalgesiaSpinal Anesthesia
Rawalpindi Medical College110 enrolled1 locationNCT07088146