Phase 1 Squamous Cell Carcinoma of Head and Neck Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Carcinoma, Non-Small Cell LungSquamous Cell Carcinoma of Head and NeckHER2 Negative Breast Neoplasms+9 more
Seagen, a wholly owned subsidiary of Pfizer1,006 enrolled158 locationsNCT04389632
Recruiting
Phase 1
Neoadjuvant CADI-05 in Combination With Pembrolizumab for Surgically Resectable Locally Advanced Head and Neck Squamous Cell Carcinomas
Squamous Cell Carcinoma of Head and Neck
Fox Chase Cancer Center22 enrolled2 locationsNCT07455032
Recruiting
Phase 1
A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma
Squamous Cell Carcinoma of Head and Neck
Johnson & Johnson Enterprise Innovation Inc.30 enrolled12 locationsNCT07219212
Recruiting
Phase 1Phase 2
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
Squamous Cell Carcinoma of Head and Neck
Janssen Research & Development, LLC287 enrolled55 locationsNCT06385080
Recruiting
Phase 1
A Study of MGC026 in Participants With Advanced Solid Tumors
Advanced Solid TumorSquamous Cell Carcinoma of Head and NeckMetastatic Cancer+1 more
MacroGenics250 enrolled12 locationsNCT06242470
Recruiting
Phase 1Phase 2
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
Squamous Cell Carcinoma of Head and NeckSolid TumorColorectal Cancer (CRC)
One-carbon Therapeutics AB43 enrolled4 locationsNCT07151040
Recruiting
Phase 1Phase 2
A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma
Squamous Cell Carcinoma of Head and Neck
Sichuan Baili Pharmaceutical Co., Ltd.130 enrolled1 locationNCT05668858
Recruiting
Phase 1Phase 2
A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Squamous Cell Carcinoma of Head and NeckAdvanced Solid Tumours
Cancer Research UK167 enrolled2 locationsNCT06380816
Recruiting
Phase 1Phase 2
Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)
Prostate CancerUrothelial CarcinomaSquamous Cell Carcinoma of Head and Neck+1 more
Evopoint Biosciences Inc.204 enrolled1 locationNCT06022757