Phase 2 Squamous Cell Carcinoma of Head and Neck Clinical Trials
15 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–15 of 15 trials
Recruiting
Phase 2
5-Fluorouracil Response and Optimization STudy (The FROST Trial)
Squamous Cell Carcinoma of Head and NeckMetastatic Squamous Cell CarcinomaRecurrent Squamous Cell Carcinoma of the Head and Neck
Washington University School of Medicine46 enrolled1 locationNCT07419464
Recruiting
Phase 1Phase 2
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
Squamous Cell Carcinoma of Head and Neck
Janssen Research & Development, LLC287 enrolled55 locationsNCT06385080
Recruiting
Phase 2
Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence
Squamous Cell Carcinoma of Head and Neck
University of Arkansas100 enrolled6 locationsNCT05952934
Recruiting
Phase 2
A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)
Squamous Cell Carcinoma of Head and NeckOral Cavity CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center40 enrolled7 locationsNCT07063212
Recruiting
Phase 2
Reduction in the Number of Chemotherapy Cycles in Combination With Pembrolizumab in First-line Treatment of PD-L1-positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinomas
Squamous Cell Carcinoma of Head and Neck
Institut Claudius Regaud86 enrolled14 locationsNCT06557889
Recruiting
Phase 1Phase 2
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
Squamous Cell Carcinoma of Head and NeckSolid TumorColorectal Cancer (CRC)
One-carbon Therapeutics AB43 enrolled4 locationsNCT07151040
Recruiting
Phase 2
5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC
Squamous Cell Carcinoma of Head and Neck
Barbara Burtness50 enrolled1 locationNCT05317000
Recruiting
Phase 1Phase 2
A Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma
Squamous Cell Carcinoma of Head and Neck
Sichuan Baili Pharmaceutical Co., Ltd.130 enrolled1 locationNCT05668858
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of MRG003 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
Shanghai Miracogen Inc.116 enrolled1 locationNCT04868162
Recruiting
Phase 2
Single-Arm Exploratory Study of PD-L1 Antibody Plus Neoadjuvant Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma
Squamous Cell Carcinoma of Head and Neck
Xiuping Ding69 enrolled1 locationNCT07055841
Recruiting
Phase 2
Study of TPEx Followed by a Maintenance With Avelumab and Cetuximab in First Line Recurrent or Metastatic Squamous Cell Carcinoma of the H&N
Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
Groupe Oncologie Radiotherapie Tete et Cou70 enrolled1 locationNCT06640725
Recruiting
Phase 2
European Larynx Organ Preservation Study (ELOS) [MK-3475-C44]
Squamous Cell Carcinoma of Head and NeckLaryngeal CancerSquamous Cell Carcinoma of Larynx+9 more
University of Leipzig140 enrolled9 locationsNCT06137378
Recruiting
Phase 1Phase 2
A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer
Squamous Cell Carcinoma of Head and NeckAdvanced Solid Tumours
Cancer Research UK167 enrolled2 locationsNCT06380816
Recruiting
Phase 2
Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
MelanomaSquamous Cell Carcinoma of Head and Neck
IO Biotech60 enrolled15 locationsNCT05280314
Recruiting
Phase 1Phase 2
Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)
Prostate CancerUrothelial CarcinomaSquamous Cell Carcinoma of Head and Neck+1 more
Evopoint Biosciences Inc.204 enrolled1 locationNCT06022757