Early Phase 1 Squamous Cell Carcinoma Clinical Trials
14 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–14 of 14 trials
Recruiting
Early Phase 1
Intratumoral Injection of Standard Universal Donor Expanded Natural Killer Cells and TGF-beta Imprinted Natural Killer Cells for the Treatment of Skin Squamous Cell Carcinoma and Basal Cell Carcinoma
Skin Squamous Cell CarcinomaSkin Basal Cell CarcinomaSkin Nodular Basal Cell Carcinoma
Kirsten Johnson40 enrolled1 locationNCT07144384
Recruiting
Early Phase 1
Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers
Head and Neck CancerSquamous Cell Carcinoma of Head and NeckSalivary Gland Cancer+1 more
Brigham and Women's Hospital30 enrolled2 locationsNCT05553782
Recruiting
Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Early Phase 1
Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
University of Alabama at Birmingham14 enrolled1 locationNCT05183048
Recruiting
Early Phase 1
Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer
Head and Neck Squamous Cell CarcinomaClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Stage III Hypopharyngeal Carcinoma AJCC v8+13 more
Emory University20 enrolled1 locationNCT06914999
Recruiting
Early Phase 1
A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision
Cutaneous Squamous Cell CancerSkin CancerCutaneous Squamous Cell Carcinoma (CSCC)
Dana-Farber Cancer Institute25 enrolled2 locationsNCT06664151
Recruiting
Early Phase 1
Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer
HNSCCSCC - Squamous Cell CarcinomaHNSCC,Larynx, Pharynx and Oral Cavity
Vanderbilt-Ingram Cancer Center18 enrolled1 locationNCT06819228
Recruiting
Early Phase 1
A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors
Head and Neck Squamous Cell CarcinomaSoft Tissue Sarcoma Adult
Pure Biologics S.A.12 enrolled1 locationNCT06700070
Recruiting
Early Phase 1
Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
University of Wisconsin, Madison12 enrolled1 locationNCT06308913
Recruiting
Early Phase 1
CivaDerm(TM) Surface Therapy Pilot Study
Basal Cell CarcinomaSquamous Cell Carcinoma of the Skin
CivaTech Oncology10 enrolled1 locationNCT04480645
Recruiting
Early Phase 1
PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC
Head and Neck Squamous Cell Carcinoma
Presage Biosciences15 enrolled7 locationsNCT06366451
Recruiting
Early Phase 1
Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of IPM514 in Patients with Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma
Peking University74 enrolled1 locationNCT06690476
Recruiting
Early Phase 1
Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy
Head and Neck Squamous Cell CarcinomaBrain Metastases
Vanderbilt-Ingram Cancer Center48 enrolled1 locationNCT05996432
Not Yet Recruiting
Early Phase 1
A Pilot Study of Cetuximab Radiolabelled with Gallium-68, Lutetium-177 or Rhenium-188 as a Novel Radioimmunotherapy for Advanced Head and Neck Cancer: A New Adjunct to Multi-modality Treatment.
Head and Neck Squamous Cell Carcinoma
Dr Timothy Marr30 enrolled1 locationACTRN12614000491662