Phase 3 SURGICAL Clinical Trials
25 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 25 trials
Recruiting
Phase 3
Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery
Surgical Blood LossTransfusion-dependent AnemiaAbdomen Disease
Ulrich Ronellenfitsch, MD850 enrolled2 locationsNCT06414031
Recruiting
Phase 3
Tranexamic Acid in Adult Spinal Deformity Surgery
Blood Loss, SurgicalSpinal DeformityDegenerative Lumbar Spinal Stenosis
Hospital for Special Surgery, New York100 enrolled1 locationNCT03553186
Recruiting
Phase 3
A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199
Recruiting
Phase 3
Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
Surgical Site Infections
Ondine Biomedical Inc.4,514 enrolled14 locationsNCT06702878
Recruiting
Phase 3
Efficacy of EXPAREL vs. Bupivacaine
Total Ankle ArthroplastyPostsurgical Analgesia
Emory University104 enrolled1 locationNCT07212114
Recruiting
Phase 3
Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty
postsurgical pain
KAZM Pharmaceuticals Inc.288 enrolled2 locationsNCT06202989
Recruiting
Phase 3
Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections
Surgical Site Infection
Loma Linda University1,100 enrolled1 locationNCT06363877
Recruiting
Phase 3
The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal
Surgical wound infection
The Cooper Health System848 enrolled1 locationNCT07142408
Recruiting
Phase 2Phase 3
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
Pain, PostoperativeHernia, UmbilicalClonidine+2 more
Universidade Federal do Rio de Janeiro62 enrolled1 locationNCT07062497
Recruiting
Phase 2Phase 3
Human Penile Allotransplantation
Wounds and InjuriesAmputationAmputation, Traumatic+6 more
Johns Hopkins University60 enrolled1 locationNCT02395497
Recruiting
Phase 2Phase 3
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
SeromaSurgical Site InfectionSurgical Wound+5 more
Dow University of Health Sciences200 enrolled1 locationNCT05989386
Recruiting
Phase 3
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT
Post Operative Surgical Site Infection
Major Extremity Trauma Research Consortium1,200 enrolled31 locationsNCT04678154
Recruiting
Phase 2Phase 3
Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section
postsurgical painCesarean SectionChronic post-surgical pain
Dalin Tzu Chi General Hospital120 enrolled1 locationNCT06344169
Recruiting
Phase 3
Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery
Surgical wound infectionAnesthesiaPathologic Processes+9 more
University of Birmingham12,942 enrolled37 locationsNCT04256798
Recruiting
Phase 2Phase 3
Multicenter Study Protocol: Research on Evaluation and Detection of Surgical Wound Complications with AI-based Recognition. (REDSCAR-trial)
Surgical wound infection
Universitat de les Illes Balears168 enrolled5 locationsNCT06771726
Recruiting
Phase 3
Broad-spectrum Antibiotic Prophylaxis in Tumor and Infected Orthopedic Surgery
Surgical Site InfectionMicrobial ColonizationAntibiotic Resistant Infection
Balgrist University Hospital1,100 enrolled1 locationNCT05502380
Recruiting
Phase 3
Povidone-iodine vs Saline Solution in Colorectal Surgeries and Its Effects on the Surgical Site Infection
Surgical Site Infection
Hospital de Clinicas de Porto Alegre228 enrolled1 locationNCT06302335
Recruiting
Phase 3
Comparisons of Metabolic Effect of Sleeve Gastrectomy With Duodenojejunal Bypass and Sleeve Gastrectomy (MEDUSA): A Multicenter Randomized Controlled Trial
Bariatric SurgeryDiabetes Mellitus, Type 2Surgical Procedures, Operative+1 more
Seoul National University Bundang Hospital130 enrolled1 locationNCT05211375
Active
Phase 3Phase 4
Reduction Of Chronic Post-surgical Pain with Ketamine - ROCKet Trial
Chronic post-surgical pain
The University of Melbourne4,884 enrolled35 locationsACTRN12617001619336
Completed
Phase 3Phase 4
Reduction Of Chronic Post-surgical Pain with Ketamine – A Pilot Study
Chronic post-surgical pain
Austin Health80 enrolled1 locationACTRN12614000247673