RecruitingPhase 3NCT06302335

Povidone-iodine vs Saline Solution in Colorectal Surgeries and Its Effects on the Surgical Site Infection

Intraoperative Irrigation of the Surgical Incision With Povidone-iodine vs Saline Solution in Colorectal Surgeries and Its Effects on the Surgical Site Infection


Sponsor

Hospital de Clinicas de Porto Alegre

Enrollment

228 participants

Start Date

Jan 2, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Considering the relatively high incidence of surgical site infection (SSI) in colorectal surgery, this trial will compare rates of SSI in patients undergoing colorectal resections followed by surgical wound irrigation with povidone-iodine versus the group of patients undergoing surgical wound irrigation with saline solution. The trial will be conducted in a large university hospital in Southern Brazil.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Patients older than 18 years of age diagnosed with benign or malignant colorectal diseases undergoing elective open or video-assisted colectomy or proctectomy (resection) at the Hospital de Clinicas de Porto Alegre - Division of Coloproctology.

Exclusion Criteria5

  • age under 18;
  • surgery classified as dirty;
  • urgent/emergency surgery;
  • patients undergoing multi-visceral resections (pelvic exenteration or partial resection of any adjacent organ);
  • known allergy to iodine.

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Interventions

DRUGPovidone-iodine

Application of Povidone-iodine to the surgical wound of patients submitted to colorectal resections.

DRUGSaline solution

Application of saline solution to the surgical wound of patients submitted to colorectal resections.


Locations(1)

Hospital de Clinicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

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NCT06302335


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