Phase 3 Syndrome Clinical Trials

198 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 198 trials

Recruiting
Phase 2Phase 3

The Treatment Effects of Empagliflozin on Renal Outcomes in Cardiorenal Syndrome Type 1

Empagliflozin in Cardiorenal Syndrome Type 1
Chulalongkorn University200 enrolled1 locationNCT06030843
Recruiting
Phase 3

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

Myelodysplastic SyndromeAnemia
Takeda300 enrolled154 locationsNCT07422480
Recruiting
Phase 3

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Dravet Syndrome
Longboard Pharmaceuticals160 enrolled101 locationsNCT06660394
Recruiting
Phase 2Phase 3

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

Mucopolysaccharidosis IIIMPS IIIASanfilippo Syndrome+1 more
Ultragenyx Pharmaceutical Inc36 enrolled5 locationsNCT02716246
Recruiting
Phase 3

A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome

Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited160 enrolled9 locationsNCT07281079
Recruiting
Phase 3

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

Complex Regional Pain Syndrome Type I
Ambros Therapeutics, Inc.270 enrolled12 locationsNCT07210515
Recruiting
Phase 3

Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis

Acute Coronary SyndromeTuberculosisPulmonary Hypertension (Diagnosis)
National University Hospital, Singapore150 enrolled6 locationsNCT05473520
Recruiting
Phase 2Phase 3

SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome

Nephrotic Syndrome
Mansoura University75 enrolled1 locationNCT07214818
Recruiting
Phase 2Phase 3

RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy

DermatomyositisIdiopathic Inflammatory MyopathyAnti-synthetase Syndrome+5 more
Cabaletta Bio74 enrolled35 locationsNCT06154252
Recruiting
Phase 3

Comparing High and lOw-dose asPirin With Dual anTIplatelet Therapy for Three Months Using prasUgrel and aSpirin Following Coronary Artery Bypass Grafting. (OPTIMUS-CABG Trial)

Chronic Coronary SyndromeStable Coronary Artery Disease CAD
Dolnośląskie Centrum Chorób Serca im.prof. Zbigniewa Religi MEDINET Sp. z o.o.1,703 enrolled18 locationsNCT07195149
Recruiting
Phase 2Phase 3

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Interstitial CystitisPainful Bladder SyndromePainful Bladder Syndrome (PBS)
David Sheyn100 enrolled1 locationNCT06096597
Recruiting
Phase 2Phase 3

Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome

Mechanical Ventilation ComplicationAcute Respiratory Distress SyndromeSedation Complication
Guy's and St Thomas' NHS Foundation Trust20 enrolled1 locationNCT06014138
Recruiting
Phase 3

Olanzapine in the Prevention and Treatment of Anorexia-Cachexia Syndrome in Patients Receiving Neoadjuvant/Preoperative Chemotherapy

OncologyCachexia-Anorexia SyndromeOncology Patients Receiving Chemotherapy
Blokhin's Russian Cancer Research Center100 enrolled1 locationNCT07633236
Recruiting
Phase 3

Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients

Poly Cystic Ovary Syndrome
Beni-Suef University180 enrolled1 locationNCT07630779
Recruiting
Phase 2Phase 3

Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms

Urinary IncontinenceOveractive BladderUrologic Diseases+1 more
Northwestern University66 enrolled1 locationNCT05878951
Recruiting
Phase 3

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals65 enrolled9 locationsNCT05795140
Recruiting
Phase 2Phase 3

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

Primary HyperparathyroidismParathyroid CancerMultiple Endocrine Neoplasias+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)193 enrolled1 locationNCT07444723
Not Yet Recruiting
Phase 3

A Multicenter, Phase 2/3, Dose Range Finding Study to Evaluate the Efficacy and Safety of Atumelnant in Adults with ACTH-Dependent Cushing’s syndrome (ADCS) Including an Open-Label Extension for Long-Term Assessment (EQUILIBRIUM ADCS) – Part C

ACTH-Dependent Cushing’s syndrome (ADCS)
Crinetics Pharmaceuticals, Inc.201 enrolled17 locationsACTRN12626000648325
Not Yet Recruiting
Phase 3

A Multicenter, Phase 2/3, Dose Range Finding Study to Evaluate the Efficacy and Safety of Atumelnant in Adults with ACTH-Dependent Cushing’s syndrome (ADCS) Including an Open-Label Extension for Long-Term Assessment (EQUILIBRIUM ADCS) – Part B

ACTH-Dependent Cushing’s syndrome (ADCS)
Crinetics Pharmaceuticals, Inc.129 enrolled17 locationsACTRN12626000647336
Recruiting
Phase 3

A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

Dravet Syndrome
Stoke Therapeutics, Inc170 enrolled61 locationsNCT06872125