TEN Clinical Trials in Boston, Massachusetts

108 recruitingBoston, Massachusetts

Showing 120 of 108 trials

Recruiting
Phase 2Phase 3

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

Extensive Stage Lung Small Cell Carcinoma
National Cancer Institute (NCI)138 enrolled416 locationsNCT04402788
Recruiting
Phase 3

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Small Cell Lung CancerExtensive-stage Small-cell Lung Cancer
Amgen330 enrolled158 locationsNCT07005128
Recruiting

Natural History Study of Synucleinopathies

Multiple System AtrophyParkinson DiseaseDementia With Lewy Bodies+5 more
NYU Langone Health800 enrolled8 locationsNCT01799915
Recruiting
Phase 1

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Extensive-stage Small-cell Lung Cancer
Amgen380 enrolled19 locationsNCT07037758
Recruiting
Phase 2

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

Chronic Obstructive Pulmonary DiseaseDyspneaPulmonary Hypertension
VA Office of Research and Development126 enrolled5 locationsNCT05937854
Recruiting

Project: Every Child for Younger Patients With Cancer

Malignant Solid NeoplasmNeuroendocrine NeoplasmCentral Nervous System Neoplasm+15 more
Children's Oncology Group75,000 enrolled278 locationsNCT02402244
Recruiting
Phase 1Phase 2

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

Colorectal, CancerStenosisFibrosis, Liver+4 more
Massachusetts General Hospital80 enrolled1 locationNCT05692024
Recruiting

Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

Premature BirthInfant, Extremely PrematureObstetric Labor, Premature+2 more
The University of Texas Health Science Center, Houston5,000 enrolled51 locationsNCT05685745
Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Heart FailurePainInsomnia+22 more
Duke University5,000 enrolled51 locationsNCT04278404
Recruiting
Phase 2

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

Extensive Stage Lung Small Cell CarcinomaLung Small Cell Carcinoma, A SubtypeLung Small Cell Carcinoma, I Subtype+2 more
SWOG Cancer Research Network900 enrolled148 locationsNCT06769126
Recruiting
Not Applicable

Home Hospital for Suddenly Ill Adults

Heart FailureAsthmaChronic Kidney Diseases+6 more
Brigham and Women's Hospital3,000 enrolled2 locationsNCT03524222
Recruiting
Phase 3

LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF

Pulmonary Hypertension
Tenax Therapeutics, Inc.230 enrolled44 locationsNCT05983250
Recruiting
Phase 1

A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Breast CancerColorectal, CancerOvarian Cancer+6 more
IDEAYA Biosciences216 enrolled27 locationsNCT05787587
Recruiting

The CurePSP Genetics Program

Multiple System Atrophy, Parkinsonian TypeMultiple System Atrophy, Cerebellar TypeMultiple System Atrophy+15 more
Massachusetts General Hospital1,000 enrolled1 locationNCT06647641
Recruiting
Not Applicable

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)

Heart FailureGroup 2 Pulmonary Hypertension
Gradient Denervation Technologies50 enrolled8 locationsNCT06052072
Recruiting

The Myelin Disorders Biorepository Project

AdrenoleukodystrophyCockayne SyndromeRefsum Disease+63 more
Children's Hospital of Philadelphia12,000 enrolled23 locationsNCT03047369
Recruiting
Not Applicable

Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension

HypertensionMultiple Sclerosis
University of Massachusetts, Boston80 enrolled1 locationNCT06554340
Recruiting
Not Applicable

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

ObesityPregnancyDepression+4 more
Massachusetts General Hospital1,320 enrolled1 locationNCT06557005
Recruiting
Phase 3

S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

Lung Small Cell CarcinomaExtensive Stage Lung Small Cell CarcinomaLimited Stage Lung Small Cell Carcinoma
SWOG Cancer Research Network668 enrolled446 locationsNCT04155034
Recruiting
Phase 1

DLL3-Directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer

Small Cell Lung Cancer Extensive StageLarge Cell Neuroendocrine Carcinoma of the Lung
Legend Biotech USA Inc41 enrolled4 locationsNCT05680922